SML3061

BSJ-04-122

>97% (HPLC)

• 別名: N-(2-((5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)phenyl)acrylamide
• 実験式（ヒル表記法）: C₁₅H₁₂ClN₅O
• CAS番号: 2513289-74-0
• 分子量: 313.74
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: >97% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C

詳細

生物化学的／生理学的作用

BSJ-04-122 is a cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7) that binds to Cys247 of MKK4. It potently inhibits JNK phosphorylation. BSJ-04-122 exhibits antiproliferative effects against triple-negative breast cancer cells. Also, BSJ-04-122 enhances antiproliferative activity of JNK-IN-8.

cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7)

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable