SML2906

ERGi-USU

≥98% (HPLC)

• 別名: 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol, 1-[2-Thiazolylazo]-2-naphthol, NSC139021, TAN
• 実験式（ヒル表記法）: C₁₃H₉N₃OS
• CAS番号: 1147-56-4
• 分子量: 255.30
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: faint brown to dark red
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: −20°C
• InChI: 1S/C13H9N3OS/c17-11-6-5-9-3-1-2-4-10(9)12(11)15-16-13-14-7-8-18-13/h1-8,17H
• InChI Key: IOMXCGDXEUDZAK-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

ERGi-USU is a selective and potent inhibitor of growth of ERG positive cancer cell lines, while spearing normal prostate or endothelial cells. It potently inhibits growth of ERG positive VCaP xenografts in mice. ERGi-USU is a potent and selective ligand of the ribosomal atypical kinase RIOK2 (right open reading frame (RIO) kinase 2) that induces ribosomal stress.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3