SML2517

Tanshinone II-A sodium sulfonate

≥95%

• 別名: 6,7,8,9,10,11-hexahydro-1,6,6-Trimethyl-10,11-dioxo-phenanthro[1,2-b]furan-2-sulfonic acid sodium salt, Sodium tanshinone IIA sulfonate, Sulfotanshinone sodium II-A, TIIAS
• 実験式（ヒル表記法）: C₁₉H₁₇NaO₆S
• CAS番号: 69659-80-9
• 分子量: 396.39
• MDL番号: MFCD09028094
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• アッセイ: ≥95%
• 形状: powder
• 色: white to beige
• 溶解性: H₂O: 2 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: CC1(C)CCCC2=C3C(C(OC(S(=O)(O[Na])=O)=C4C)=C4C(C3=O)=O)=CC=C21
• InChI: 1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1
• InChI Key: AZEZEAABTDXEHR-UHFFFAOYSA-M

詳細

生物化学的／生理学的作用

Tanshinone II A sulfonate is a water-soluble derivative of tanshinone II A that exhibits anti-inflammatory properties in rodent models of hepatitis and sepsis. Tanshinone II A sulfonate targets Ca²⁺-activated potassium channels and carboxylesterase 2. Recent studies indicate that tanshinone II A sulfonate but not tanshinone II A acts as potent negative allosteric modulator of the human purinergic receptor P2X7.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable