SML1854

Banoxantrone dihydrochloride

≥98% (HPLC)

• 別名: 1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione, AQ4N dihydrochloride
• 実験式（ヒル表記法）: C₂₂H₂₈N₄O₆ · 2HCl
• CAS番号: 252979-56-9
• 分子量: 517.40
• MDL番号: MFCD19690955
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: blue
• 溶解性: H₂O: 3 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: O=C1C2=C(C(NCC[N+](C)([O-])C)=CC=C2NCC[N+]([O-])(C)C)C(C3=C(O)C=CC(O)=C31)=O.[H]Cl.[H]Cl
• InChI: 1S/C22H28N4O6.2ClH/c1-25(2,31)11-9-23-13-5-6-14(24-10-12-26(3,4)32)18-17(13)21(29)19-15(27)7-8-16(28)20(19)22(18)30;;/h5-8,23-24,27-28H,9-12H2,1-4H3;2*1H
• InChI Key: SBWCPHUXRZRTDP-UHFFFAOYSA-N

詳細

アプリケーション

Banoxantrone dihydrochloride has been used as an organic ligand during a self-assembled metal-organic coordinated nanoparticle (Cu–OCNP/Lap) synthesis. It has also been used for the preparation of supramolecularly functionalized graphene oxide for hypoxia-activated chemotherapy of cancer.

生物化学的／生理学的作用

Banoxantrone (AQ4N) is a hypoxia-activated prodrug of topoisomerase II inhibitor AQ4 (Bioreductive AQ4 precursor).

Banoxantrone dihydrochloride enhances the anti-tumor effect caused by radiation.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable