SML1284

Efavirenz Ready Made Solution

10 mg/mL in DMSO

• 別名: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one, (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
• 実験式（ヒル表記法）: C₁₄H₉ClF₃NO₂
• CAS番号: 154598-52-4
• 分子量: 315.67
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• フォーム: DMSO solution
• 品質水準: 200
• 濃度: 10 mg/mL in DMSO
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: FC(F)(F)[C@]2(OC(=O)Nc3c2cc(cc3)Cl)C#CC1CC1
• InChI: 1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
• InChI Key: XPOQHMRABVBWPR-ZDUSSCGKSA-N

詳細

生物化学的／生理学的作用

Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI).

Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI). Efavirenz is an anti-HIV drug, commonly used in combination therapy for AIDs treatment. Efavirenz is part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.

The plasma levels of this drug can determine the failure of treatment and CNS (central nervous system) side-effects in patients infected with HIV (human immunodeficiency virus).

安全性情報

• ピクトグラム: GHS08,GHS09
• シグナルワード: Danger
• 危険有害性情報: H360,H411
• 注意書き: P202 - P273 - P280 - P308 + P313 - P391 - P405
• 危険有害性の分類: Aquatic Chronic 2 - Repr. 1B
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): 188.6 °F
• 引火点(℃): 87 °C