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製品名
膵臓エラスターゼ基質,
アッセイ
≥95% (HPLC)
フォーム
lyophilized
組成
Peptide Content, ≥85%
保管条件
protect from light
保管温度
−20°C
Amino Acid Sequence
MeOSuc-Ala-Ala-Pro-Val-4-MNA
アプリケーション
Elastase(s) can be assayed and differentiated using chromogenic and fluorogenic Pro-Val peptide substrates such as Glp-Pro-Val-pNA and MeOSuc-Ala-Ala-Pro-Val-4-MNA.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
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J V Edwards et al.
The journal of peptide research : official journal of the American Peptide Society, 66(4), 160-168 (2005-09-06)
An assessment of elastase-substrate kinetics and adsorption at the solid-liquid interface of peptide-bound resin was made in an approach to the solid-phase detection of human neutrophil elastase (HNE), which is found in high concentration in chronic wound fluid. N-succinyl-alanine-alanine-proline-valine-p-nitroanilide (suc-Ala-Ala-Pro-Val-pNA)
G Dent et al.
Lung, 173(3), 165-175 (1995-01-01)
Elastase and antielastase activities were measured in bronchoalveolar lavage fluid (BALF) and their relationship to bronchoalveolar lavage (BAL) neutrophil numbers was assessed in order to determine whether the elevated BAL neutrophil count can predict a shift in the elastase/antielastase balance.
D Nunley et al.
American journal of respiratory and critical care medicine, 159(1), 258-261 (1999-01-05)
Large numbers of neutrophils with unopposed neutrophil elastase (NE) proteolytic activity are found in lower respiratory tract secretions from most patients with advanced cystic fibrosis (CF). To determine whether antielastase defenses may be overwhelmed in epithelial lining fluid after lung
Pier Carlo Braga et al.
Pharmacology, 77(3), 150-154 (2006-07-11)
Erdosteine is a mucolytic drug whose metabolization gives rise to an active metabolite with an SH group (Met I), which reduces neutrophil release of reactive oxygen species and the peroxynitrite generated by the reaction of superoxide anion with nitric oxide
H Moriuchi et al.
Intensive care medicine, 24(7), 709-715 (1998-08-29)
Oleic acid (OA) can produce a lung injury similar to the adult respiratory distress syndrome (ARDS). Elastase and superoxides are thought to have an effect in ARDS. However, the effect that elastase and superoxide have in OA lung injury is
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