SAB5700352

Anti-Phospho-EIF4EBP1-T36 antibody produced in rabbit

• 別名: 4E-BP1, 4EBP1, BP-1, EIF4EBP1, PHAS-I
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: 12
• 化学種の反応性: human, mouse, rat
• 濃度: 3.42 mg/ml
• テクニック: immunohistochemistry: 1:50-1:100; western blot: 1:500-1:2000
• UniProtアクセッション番号: Q13541
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pThr36)
• 遺伝子情報: human ... EIF4EBP1(1978)

詳細

詳細

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

免疫原

A phospho specific peptide corresponding to residues surrounding T36 of human EIF4EBP1

物理的形状

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保管および安定性

Store at -20℃. Avoid freeze / thaw cycles.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable