EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
Synonyms:
4E-BP1, 4EBP1, BP-1, PHAS-I
Species:
Human EIF4EBP1 (1978), Mouse Eif4ebp1 (13685), Rat Eif4ebp1 (116636), Zebrafish eif4ebp1 (799566), dog EIF4EBP1 (475590), cow EIF4EBP1 (509613), domestic cat EIF4EBP1 (101088571), chicken EIF4EBP1 (426773), naked mole-rat Eif4ebp1 (101710614), domestic guinea pig Eif4ebp1 (100733182) ...More
UniProtKB ID:
Gene ID:
- Human(1978) Summary: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
- Mouse(13685) eukaryotic translation initiation factor 4E binding protein 1
- Rat(116636) eukaryotic translation initiation factor 4E binding protein 1
- Zebrafish(799566) eukaryotic translation initiation factor 4E binding protein 1
- dog(475590) eukaryotic translation initiation factor 4E binding protein 1
- cow(509613) eukaryotic translation initiation factor 4E binding protein 1
- domestic cat(101088571) eukaryotic translation initiation factor 4E binding protein 1
- chicken(426773) eukaryotic translation initiation factor 4E binding protein 1
- naked mole-rat(101710614) eukaryotic translation initiation factor 4E binding protein 1
- domestic guinea pig(100733182) eukaryotic translation initiation factor 4E binding protein 1
- Goat(100861097) eukaryotic translation initiation factor 4E binding protein 1
- sheep(101111426) eukaryotic translation initiation factor 4E binding protein 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-EIF4EBP1 (Ab-45) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-4E-BP1 (pThr70) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Proteins
Product Number
Description
Species
4EBP1, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
4EBP1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human