SAB5500082

Anti-Chromogranin A antibody, Rabbit monoclonal

clone SP12, recombinant, expressed in proprietary host, tissue culture supernatant

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• リコンビナント: expressed in proprietary host
• 結合体: unconjugated
• 抗体製品の状態: tissue culture supernatant
• 抗体製品タイプ: primary antibodies
• クローン: SP12, monoclonal
• 化学種の反応性: human (tested)
• 化学種の反応性（ホモロジーによる予測）: bovine, pig
• テクニック: immunohistochemistry: 1:200
• アイソタイプ: IgG
• UniProtアクセッション番号: P10645
• 輸送温度: wet ice
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CHGA(1113)

詳細

詳細

Chromogranin A (CgA) is a circulating protein liberated by the neuroendocrine system. It is a glycoprotein that is located on human chromosome 14.

Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

免疫原

Recombinant protein encoding human chromogranin A.

生物化学的／生理学的作用

Chromogranin A (CgA) controls vascular physiology and angiogenesis. It modulates the storage and liberation of catecholamine via intracellular (vesiculogenic) and extracellular (catecholamine release–inhibitory) mechanisms. CHGA is essential to generate catecholamine secretory vesicles in chromaffin-lineage PC12 cells and is required to promote a regulated secretion system in nonsecretory cells.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable