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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 2888 kDa
化学種の反応性
rat, human, mouse
濃度
~1 mg/mL
テクニック
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... MTOR(2475)
詳細
Anti-MTOR antibody detects endogenous levels of total MTOR protein.
The mechanistic/mammalian target of rapamycin (mTOR) is a serine/threonine kinase. It is a member of the phosphatidylinositide 3-kinases (PI 3-kinases or PI3Ks) family. It is mapped to human chromosome 1p36.22.
免疫原
The antiserum was produced against synthesized peptide derived from human mTOR.
Immunogen Range: 2447-2496
Immunogen Range: 2447-2496
アプリケーション
Anti-MTOR, C-Terminal antibody has been used in western blotting.
生物化学的/生理学的作用
The mechanistic/mammalian target of rapamycin (mTOR) controls protein translation, cell growth, survival, invasion and metabolism. It acts as an intracellular signalling regulator which links the extracellular events to the intracellular process. mTOR also acts on the protein synthesis machinery.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(4), 1723-1734 (2018-08-06)
Autophagy is a process of evolutionarily conservative degradation, which could maintain cellular homeostasis and cope with various types of stress. LncRNAs are considered as competing endogenous RNAs (ceRNAs) contributing to autophagy. GAS5 has been suggested as a new potential factor
Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition
RNA (2017)
The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma
Cancer Letters, 400, 110-116 (2017)
Expression of the mTOR pathway regulators in human pituitary adenomas indicates the clinical course
Anticancer Research, 33(8), 3123-3131 (2013)
Journal of cellular physiology, 234(5), 7420-7434 (2018-10-27)
Long noncoding RNA urothelial carcinoma associated 1 (UCA1) has been implicated in the growth and metastasis of colorectal cancer (CRC), and autophagy contributes to tumorigenesis and cancer cell survival. However, the regulatory role of UCA1 in CRC cell viability by
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