SAB4500802

Anti-AKT antibody produced in rabbit

affinity isolated antibody

• 別名: PKB
• MDL番号: MFCD03096597
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 55 kDa
• 化学種の反応性: human, rat, mouse
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBIアクセッション番号: P31749
• UniProtアクセッション番号: P31749
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... AKT1(207)

詳細

詳細

AKT1 (AKT serine/threonine kinase 1) is also called as v-akt murine thymoma viral oncogene homolog 1 and PKBα(protein kinase B). It is upregulated in liver, muscle and adipocytes. AKT1 gene is mapped to human chromosome 14q32. It is a member of AKT family that has an amino-terminal pleckstrin homology (PH) domain, a short α-helical linker and a carboxyl-terminal kinase domain.

Anti-AKT Antibody detects endogenous levels of total AKT protein.

免疫原

The antiserum was produced against synthesized peptide derived from human Akt.

Immunogen Range: 292-341

アプリケーション

Anti-AKT1 (Ab-473) antibody has been used in western blotting and immunostaining.

生物化学的／生理学的作用

AKT1 (AKT serine/threonine kinase 1) controls the survival of cell and anti-apoptotic actions that attack the pathogenesis of several cancers , hence it plays a crucial role in tumorigenesis. In mice, AKT1 is essential for normal development.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable