SAB4200764

Anti-Dystrophin antibody, Mouse monoclonal

clone MANDYS8, purified from hybridoma cell culture

• 別名: Anti-DMD
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: MANDYS8, monoclonal
• 形状: buffered aqueous solution
• 分子量: ~427 kDa
• 化学種の反応性: porcine, rabbit, mouse, rat, human
• 強化検証: independent; Learn more about Antibody Enhanced Validation
• 濃度: ~1.0 mg/mL
• テクニック: immunoblotting: suitable; immunohistochemistry: 5-10 μg/mL using acetone fixed rat tongue frozen sections
• アイソタイプ: IgG2b
• UniProtアクセッション番号: P11532
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... DMD(1756)

詳細

詳細

Anti-Dystrophin antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with fragment of recombinant human dystrophin. Dystrophin is a 427 kD protein which joins the actin cytoskeleton to laminin. It possesses multiple domains and is localized to the extracellular matrix. Dystrophin contains NH2-terminal domain for actin binding. The C-terminal domain interacts with dystrophin associated protein (DAP).

Dystrophin is a rod-shaped cytoskeletal protein located to the periphery (plasma membrane) of normal striated muscle fibers.

特異性

Anti-Dystrophin antibody, Mouse monoclonal specifically recognizes an epitope located on the rod domain of the human dystrophin molecule.

免疫原

recombinant human dystrophin

アプリケーション

Anti-Dystrophin antibody, Mouse monoclonal has been used in immunoblotting and immunohistochemistry.

生物化学的／生理学的作用

Dystrophin is known to prevent muscle fibre injury due to contraction.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.

その他情報

This product is for R&D use only, not for drug, household, or other uses.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable