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交差性
human
包装
kit of 96 wells (12 strips x 8 wells)
テクニック
ELISA: suitable
入力
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 6.14-1500 pg/mL
検出方法
colorimetric
輸送温度
wet ice
保管温度
−20°C
遺伝子情報
human ... F3(2152)
詳細
The antibody pair provided in this kit recognizes human Coagulation Factor III/Tissue Factor.
Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3. TF has been shown to exist in two forms, namely membrane-bound and soluble TF. The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).
Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3. TF has been shown to exist in two forms, namely membrane-bound and soluble TF. The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).
アプリケーション
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human F3 / Tissue Factor ELISA Kit has been used to measure the concentration of soluble tissue factor (TF) expressed in human umbilical vein smooth muscle cells (HUVSMCs).
Human F3 / Tissue Factor ELISA Kit has been used to measure the concentration of soluble tissue factor (TF) expressed in human umbilical vein smooth muscle cells (HUVSMCs).
生物化学的／生理学的作用
Tissue factor (TF) interacts with the zymogen factor VII (VII) and its activated form VIIa, and initiates blood coagulation protease cascade. The encoded protein is involved in the pathogenesis of cardiovascular diseases, such as hypertension, atherosclerosis, acute coronary syndrome and restenosis. Thus, it is considered to be a potential therapeutic target for cardiovascular diseases.
シグナルワード
Warning
危険有害性情報
注意書き
危険有害性の分類
Met. Corr. 1
保管分類コード
8A - Combustible corrosive hazardous materials
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
毒物及び劇物取締法
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PRTR
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消防法
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労働安全衛生法名称等を表示すべき危険物及び有害物
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労働安全衛生法名称等を通知すべき危険物及び有害物
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カルタヘナ法
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Jan Code
キットコンポーネントの情報を参照してください
Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule.
Bromberg M E, et al.
Thrombosis and Haemostasis, 82(01), 88-92 (1999)
Magdalena Markowicz-Piasecka et al.
Scientific reports, 9(1), 6573-6573 (2019-04-27)
Type 2 diabetes mellitus (T2DM) is a multi-factorial disease which can cause multiple organ dysfunction, including that of the vascular endothelium. The aim of the present study was to evaluate the effects of metformin, and its sulfenamide and sulfonamide derivatives
Daniel D'Oliveira Silva et al.
International braz j urol : official journal of the Brazilian Society of Urology, 44(1), 38-44 (2017-07-21)
to determine the usefulness of serum TF as a potential marker for patients with clear cell RCC. prospective study of 30 patients with clear cell RCC submitted to nephrectomy and 16 controls without clear cell RCC treated surgically for other
Rashi Singhal et al.
Clinical immunology (Orlando, Fla.), 175, 133-142 (2017-01-01)
Monocytes and macrophage combat infections and maintain homeostatic balance by engulfing microbes and apoptotic cells, and releasing inflammatory cytokines. Studies have described that these cells develop anti-inflammatory properties upon recycling the free-hemoglobin (Hb) in hemolytic conditions. While investigating the phenotype
Gordana Kocic et al.
Cancers, 12(10) (2020-10-18)
Balkan endemic nephropathy (BEN) is a chronic tubulointerstitial disease frequently accompanied by urothelial carcinoma (UC). In light of the increased UC incidence and the markers observed in BEN patients with developed UC, the aim of the current case-control study is
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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