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化学種の反応性
human
包装
kit of 96 wells (12 strips x 8 wells)
テクニック
ELISA: suitable
capture ELISA: suitable
入力
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 150 pg/mL
standard curve range: 0.137-100 ng/mL
検出方法
colorimetric
輸送温度
wet ice
保管温度
−20°C
遺伝子情報
human ... MMP7(4316)
詳細
The human MMP-7 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-7 in cell culture supernatants. Matrix metalloproteinase-7 (MMP-7)/matrilysin is a small proteolytic enzyme. It secretes zinc- and calcium-dependent endopeptidase. It is expressed in normal endometrial, bronchial, ductal, skin glandular epithelial, urogenital, and gastrointestinal tissues. MMP-7 plays a key role in cell proliferation, migration, invasion, and apoptosis. Elevated expression of MMP-7 is seen in several cancers, such as esophageal, gastric, gallbladder, pancreatic, colorectal, bladder, ovarian, breast, lung, and melanoma.
免疫原
Recombinant Human MMP7
アプリケーション
Human MMP-7 ELISA Kit has been used in ELISA to measure the recovery of the cancer biomarkers/MMP-7 in isothermally vitrified samples. It has also been used in ELISA to determine MMP7 concentrations in multiple myeloma (MM) cell culture supernatants.
その他情報
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
シグナルワード
Warning
危険有害性情報
注意書き
危険有害性の分類
Met. Corr. 1
保管分類コード
8B - Non-combustible corrosive hazardous materials
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
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Jan Code
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Hai-Yang Liao et al.
Clinical biochemistry, 92, 9-18 (2021-03-14)
Matrix metalloproteinase-7 (MMP-7) is a small proteolytic enzyme that secretes zinc and calcium endopeptidases. It can degrade a variety of extracellular matrix substrates and other substrates and plays important regulatory roles in many human pathophysiological processes. Since its discovery, MMP-7
Guobao Wang et al.
Arthritis & rheumatology (Hoboken, N.J.), 73(2), 265-275 (2020-09-07)
Flares of lupus nephritis (LN) are frequent and associated with impaired renal prognosis. One major management obstacle in LN flare is the lack of effective methods to identify at-risk patients earlier in their disease course. This study was undertaken to
Jian Zhang et al.
Kidney & blood pressure research, 42(3), 541-552 (2017-09-19)
In view of the latest findings that matrix metalloproteinase-7 (MMP-7) acted as a vital marker and pathogenic mediator of renal fibrosis in a murine model, we hypothesized that serum MMP-7 level might serve as a noninvasive prognostic biomarker in IgA
Anita M Tuomainen et al.
European journal of preventive cardiology, 21(7), 806-812 (2012-10-20)
Extracellular matrix-degrading proteinases are upregulated in atherosclerotic lesions and can contribute to subsequent pathological events. In the present nested case-control study, we investigated the association of serum concentrations of matrix metalloproteinases MMP-7, MMP-8, and MMP-13, tissue inhibitor of metalloproteinase-1 (TIMP-1)
Fan Fang et al.
Disease markers, 2019, 9217571-9217571 (2019-12-13)
Early detection of patients at high risk for progressive acute kidney injury (AKI) after cardiac surgery remains a major challenge. We aim to evaluate the utility of urinary matrix metalloproteinase-7 (uMMP-7) and other reported biomarkers for predicting AKI progression during
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