R5258

Riboflavin Binding Protein from chicken egg white

lyophilized powder

• 別名: Binding Protein, Chicken Egg White Protein, Riboflavin Protein
• UNSPSCコード: 12352202
• NACRES: NA.26

特性

• 由来生物: chicken egg white
• 品質水準: 200
• 形状: lyophilized powder
• 濃度: ≥50% protein (biuret)
• UniProtアクセッション番号: P02752
• 保管温度: −20°C
• 遺伝子情報: chicken ... RBP(396449)

詳細

詳細

Riboflavin Binding Protein (RBP) comprises of 19 cysteines and corresponds to a molecular weight of 30 kDa. Egg white RBP is produced in the oviduct cells. Chicken egg white RBP contains an N-terminal ligand binding domain and a C-terminal phosphorylated motif.

Riboflavin binding protein (RBP) transports riboflavin through the bloodstream of the laying hen into the eggs, where the vitamin is essential for embryonic growth and development. RBP consists of a single polypeptide chain containing 9 disulfide bonds. It is a glycoprotein containing ~14% carbohydrate, with sugar moieties including galactose, mannose and glucosamine, and is phosphorylated.

アプリケーション

Riboflavin Binding Protein from chicken egg white may be used in fluorescence quenching experiments.

生物化学的／生理学的作用

Riboflavin Binding Protein (RBP) is crucial for normal embryo development. RBP interacts with riboflavin and its analogs. The RBP-riboflavin complex is stabilized by interaction between the isoalloxazyne ring of riboflavin and the tyrosine 75 and tryptophan 156 of residues of RBP. RBP elicits sweet supressing functionality and may interact with the sweet taste receptor.

Riboflavin binding protein binds to flavokinase and regulates its activity.

調製ノート

Supplied as the riboflavin-depleted apo-form.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)