R1406

RIPK2(1-299)、活性型、GSTタグ融合 ヒト

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 別名: CARD3, CARDIAK, RICK, RIP2
• UNSPSCコード: 51111800
• NACRES: NA.32

特性

• リコンビナント: expressed in baculovirus infected Sf9 cells
• 品質水準: 200
• 製品種目: PRECISIO^® Kinase
• アッセイ: ≥70% (SDS-PAGE)
• フォーム: buffered aqueous glycerol solution
• 比活性: 17-23 nmol/min·mg
• 分子量: ~59 kDa
• UniProtアクセッション番号: O43353
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... RIPK2(8767)

詳細

詳細

Receptor interacting serine/threonine kinase 2 (RIPK2) or RICK is a serine/threonine kinase. It contains a kinase domain at the amino-terminal, an intermediate domain and a caspase activation and recruitment domain (CARD) at the carboxy-terminal. The gene encoding RIPK2 is localized on human chromosome 8q21.3.

生物化学的／生理学的作用

Receptor interacting serine/threonine kinase 2 (RIPK2) or RICK is activated during innate immune responses and acts as a scaffold for downstream effectors. It functions in nuclear factor-κB (NFκB) activation pathways. The protein also has roles in toll-like receptor (TLR)-signaling pathways and in the production of inflammatory cytokines.

物理的形状

50 mM Tris-HCl溶液(pH 7.5、150 mM NaCl、0.25 mM DTT、0.1 mM EGTA、0.1 mM EDTA、0.1 mM PMSF、25%グリセロール含有)。

法的情報

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)