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Merck
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主要文書

安全性情報

PLA0205

Sigma-Aldrich

Rabbit anti-CREB Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

別名:

5′-monophosphate response element-binding protein CREB, CREB, CREB-1, active transcription factor CREB, cAMP-response element-binding protein-1, cAMP-responsive element-binding protein 1, cyclic adenosine 3′, transactivator protein

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

100

抗体製品の状態

affinity purified immunoglobulin

抗体製品タイプ

primary antibodies

グレード

Powered by Bethyl Laboratories, Inc.

化学種の反応性

mouse, human

テクニック

immunohistochemistry: 1:100- 1:1,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

アクセッション番号

NP_604391.1

輸送温度

wet ice

保管温度

2-8°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

rabbit ... CREB(1385)

免疫原

The epitope recognized by PLA0205 maps to a region between residue 250 and 300 of human cAMP responsive element binding protein 1 using the numbering given in entry NP_604391.1 (GeneID 1385).

物理的形状

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

その他情報

CREB (cyclic AMP response element-binding protein) is a ubiquitously expressed transcription factor that binds cAMP response elements to regulate gene transcription for various cellular responses such as glucose homeostasis, growth-factor dependent survival, and proliferation. CREB is also implicated to play a role in memory and mood.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

PLA0205-100UL-KC:
PLA0205-100UL:

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試験成績書（COA）

Lot/Batch Number

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文書ライブラリにアクセスする

Celine I Maeder et al.
Cell, 174(6), 1436-1449 (2018-08-28)
Synaptic vesicle and active zone proteins are required for synaptogenesis. The molecular mechanisms for coordinated synthesis of these proteins are not understood. Using forward genetic screens, we identified the conserved THO nuclear export complex (THOC) as an important regulator of
Zhenglin Zhao et al.
Neuroscience letters, 567, 19-23 (2014-03-29)
The role of neuropeptide Y (NPY) in the central nucleus of amygdala (CeA) in the preventive effects of acupuncture against ethanol withdrawal-induced anxiety was investigated. Rats were treated with 3g/kg/day of ethanol for 28 days, followed by 3 days of
Shuichi Moriya et al.
Journal of cellular biochemistry, 116(1), 142-148 (2014-08-29)
As the aged population is soaring, prevalence of osteoporosis is increasing. However, the molecular basis underlying the regulation of bone mass is still incompletely understood. Sympathetic tone acts via beta2 adrenergic receptors in bone and regulates the mass of bone
Catherine M Westbom et al.
The American journal of pathology, 184(10), 2816-2827 (2014-08-12)
Malignant mesothelioma (MM) is an aggressive tumor with no treatment regimen. Previously we have demonstrated that cyclic AMP response element binding protein (CREB) is constitutively activated in MM tumor cells and tissues and plays an important role in MM pathogenesis.
Sun-Young Lee et al.
International journal of oncology, 45(2), 675-682 (2014-05-29)
Nutlin-3 which occupies the p53 binding pocket in HDM2, has been reported to activate apoptosis through both the transcriptional activity-dependent and -independent programs of p53. Transcription-independent apoptosis by nutlin-3 is triggered by p53 which is translocated to mitochondria. However, we
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