P8997

抗プリンレセプターP2X₇ (細胞外)−FITC ウサギ宿主抗体

affinity isolated antibody, lyophilized powder

• 別名: 抗P2Z抗体
• MDL番号: MFCD06798528
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: FITC conjugate
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: lyophilized powder
• 化学種の反応性: human, rat, mouse
• テクニック: flow cytometry: 10 μg/test using Jurkat T-cells
• UniProtアクセッション番号: Q99572
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... P2RX7(5027) ; mouse ... P2rx7(18439) ; rat ... P2rx7(29665)

詳細

詳細

Purinergic Receptor P2X7 is a ionotrophic ATP-gated channel responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. ATP activation of the P2RX7 leads to recruitment of pannexin pores which allow small molecules such as ATP to leak out of cells further activating of purinergic receptors and physiological responses such a spreading cytoplasmic waves of calcium.
Fluorescein isothiocyanate (FITC) is a fluorescein derivative (fluorochrome) used to tag antibodies, including secondary antibodies, for use in fluorescence-based assays and procedures. FITC excites at 495 nm and emits at 521 nm.

特異性

Rabbit polyclonal anti-Purinergic Receptor P2X7 (extracellular)−FITC antibody reacts with rat, human, and mouse purinergic receptor P2X7 (extracellular).

免疫原

マウスP2X₇レセプタ-のアミノ酸残基136-152に相当する合成ペプチドです。ヒト、マウス、ラットの配列は同一です。ウシでは14/17残基一致しています。

アプリケーション

Rabbit polyclonal anti-Purinergic Receptor P2X7 (extracellular)−FITC antibody is used to tag Purinergic Receptor P2X7 (extracellular) for detection and quantitation by fluorescence-based immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of Purinergic Receptor P2X7 (extracellular) in ATP-dependent processes such as cell lysis and calcium movement.

物理的形状

凍結乾燥品 (PBS, pH 7.4, 1%BSA, 0.05%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable