P0021

パントプラゾール ナトリウム 水和物

≥98% (HPLC)

• 別名: パントゾール 水和物, プロトニックス 水和物
• 実験式（ヒル表記法）: C₁₆H₁₄F₂N₃O₄S · Na · xH₂O
• CAS番号: 718635-09-7
• 分子量: 405.35 (anhydrous basis)
• UNSPSCコード: 12352203
• PubChem Substance ID: 329819976
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• 形状: powder
• 保管条件: desiccated
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• 色: white to off-white
• 溶解性: H₂O: ≥20 mg/mL
• オーガナイザー: Novartis
• 保管温度: −20°C
• SMILES記法: O.[Na+].COc1ccnc(CS(=O)c2nc3cc(OC(F)F)ccc3[n-]2)c1OC
• InChI: 1S/C16H14F2N3O4S.Na.H2O/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16;;/h3-7,15H,8H2,1-2H3;;1H2/q-1;+1;
• InChI Key: CGJRLPRCWSHOFU-UHFFFAOYSA-N
• 遺伝子情報: human ... ATP4A(495) , ATP4B(496)

詳細

アプリケーション

Pantoprazole sodium hydrate has been used:

• as a standard in high-performance liquid chromatography (HPLC){58
• as a prazole to study its effects on prodrug activation and human immunodeficiency virus 1 (HIV-1) inhibition
• to study its effects on breast cancer resistance protein (BCRP) inhibitors in various in vitro membrane preparations from various cell lines

生物化学的／生理学的作用

Pantoprazole has the potential to treat symptoms of heartburn and acid regurgitation. It also has been studied to treat Helicobacter pylori infection and duodenal ulcer.

Pantoprazole is a benzimidazole derivative,activated in acidic environment. It is useful in treating long term prophylaxis and acid-related disorders.

Pantoprazole is a gastric proton pump inhibitor.

特徴および利点

This compound is featured on the Acid-Sensing (Proton-gated) Ion Channels (ASICs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable