N216

モノクローナル抗Na⁺/Ca⁺交換体抗体 マウス宿主抗体

clone C2C12

• MDL番号: MFCD01865491
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品タイプ: primary antibodies
• クローン: C2C12, monoclonal
• 形状: liquid
• 分子量: antigen 120 kDa (mature exchanger); antigen 160 kDa (non-reduced); antigen 70 kDa (proteolytic fragment)
• 化学種の反応性: human, rat, canine, rabbit, guinea pig
• テクニック: immunohistochemistry (frozen sections): 1:200; immunoprecipitation (IP): suitable; western blot: 1:1,000
• アイソタイプ: IgM
• UniProtアクセッション番号: P32418
• 輸送温度: dry ice
• 保管温度: −20°C
• 遺伝子情報: human ... SLC8A1(6546)

詳細

詳細

Na⁺/Ca²⁺ exchanger is also known as solute carrier family 8 member A1 (SLC8A1) and is present in the plasma membrane. It is predicted to have nine transmembrane segments and the gene encoding SLC8A1 has three promoters.

特異性

抗体は、腎臓および心臓組織のNa⁺/Ca²⁺交換体と特異的に反応します。免疫組織化学において、形質膜の染色に加え、心臓T管膜に強い染色が認められます。この抗体は、ラット組織サンプルのイムノブロッティングには適していません。

免疫原

イヌ心臓Na⁺/Ca²⁺交換体。エピト-プは形質膜の細胞内側に位置するアミノ酸371-525の領域に存在しています。

生物化学的／生理学的作用

Na⁺/Ca²⁺ exchanger (SLC8A1, solute carrier family 8 member A1) is involved in Ca²⁺ homeostasis. Depending on physiological conditions prevailing in the cell, it can either pump out Na⁺ or Ca²⁺.

物理的形状

Solution in phosphate buffered saline, 1 mg/ml BSA containing 0.05% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)