おすすめの製品
品質水準
アッセイ
≥95% (HPLC)
溶解性
H2O: soluble
抗生物質活性スペクトル
Gram-negative bacteria
Gram-positive bacteria
作用機序
cell membrane | interferes
保管温度
−20°C
Amino Acid Sequence
Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly
詳細
Chemical structure: peptide
アプリケーション
Lactoferricin B, fragment 4-14 trifluoroacetate salt has been used to study effect of lactoferricin on cell proliferation of human colon cancer cells. It has been used in study of ultraviolet light-mediated DNA damage in human colon cancer cells.
生物化学的／生理学的作用
Lactoferricin B also suppresses liver and lung metastasis in murine melanomas and lymphomas. In addition, it causes cell death in human leukemic and carcinoma cell lines. It is effective against Escherichia coli, Salmonella enteritidis, Klebsiella pneumoniae, Proteus vulgaris, Yersinia enterocolitica, Pseudomonas aeruginosa, Campylobacter jejuni, Staphylococcus aureus, Streptococcus mutans, Corynebacterium diphtheriae, Listeria monocytogenes and Clostridium perfringens.
Antibiotic peptide in colostrum and milk that protects from bacterial infection at mucosal surfaces.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
L1290-VAR:
L1290-1MG:
L1290-BULK:
L1290-1MG-PW:
C Freiburghaus et al.
Journal of dairy science, 92(6), 2477-2484 (2009-05-19)
Food components modify the risk of cancer at a large number of sites but the mechanism of action is unknown. In the present investigation, we studied the effect of the peptide lactoferricin derived from bovine milk lactoferrin on human colon
Liv Tone Eliassen et al.
International journal of cancer, 119(3), 493-500 (2006-03-31)
Antimicrobial peptides have been shown to exert cytotoxic activity towards cancer cells through their ability to interact with negatively charged cell membranes. In this study the cytotoxic effect of the antimicrobial peptide, LfcinB was tested in a panel of human
C Freiburghaus et al.
Journal of dairy science, 95(10), 5552-5560 (2012-08-21)
Treatment of Caco-2 cells with the peptide lactoferricin(4-14), results in reduction of the growth rate by prolongation of the S phase of the cell cycle. Lactoferricin(1-25) is formed in the gut by cleavage from lactoferrin and the bioactive amino acids
W Bellamy et al.
The Journal of applied bacteriology, 73(6), 472-479 (1992-12-01)
A physiologically diverse range of Gram-positive and Gram-negative bacteria was found to be susceptible to inhibition and inactivation by lactoferricin B, a peptide produced by gastric pepsin digestion of bovine lactoferrin. The list of susceptible organisms includes Escherichia coli, Salmonella
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）