K3750

L-キヌレニン 硫酸塩

≥98% (HPLC), suitable for ligand binding assays

• 別名: β-アントラニロイル-D-アラニン, L-2-アミノ-4-(2-アミノフェニル)-4-オキソブタン酸
• 化学式: C₁₀H₁₂N₂O₃ · H₂SO₄
• CAS番号: 16055-80-4
• 分子量: 306.29
• MDL番号: MFCD00039104
• UNSPSCコード: 12352209
• PubChem Substance ID: 24896233
• NACRES: NA.26

特性

• 製品名: L-キヌレニン 硫酸塩, crystalline
• アッセイ: ≥98% (HPLC)
• 品質水準: 200
• フォーム: crystalline
• テクニック: ligand binding assay: suitable
• 色: light yellow
• 保管温度: −20°C
• SMILES記法: OS(O)(=O)=O.N[C@@H](CC(=O)c1ccccc1N)C(O)=O
• InChI: 1S/C10H12N2O3.H2O4S/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15;1-5(2,3)4/h1-4,8H,5,11-12H2,(H,14,15);(H2,1,2,3,4)/t8-;/m0./s1
• InChI Key: KAXRWMOLNJZCEW-QRPNPIFTSA-N

詳細

アプリケーション

L-Kynurenine sulfate salt has been used as a substrate to study the enzyme activity of kynurenine aminotransferase. It has also been used in the synthesis of Kyn adducts of certain amino acids .

生物化学的／生理学的作用

L-Kynurenine (L-Kyn) is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mammals, it modulates the transmission of glutamate neurotransmitter. It is also considered to be a sex-attracting pheromone in vertebrates.

L-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. L-kynurenine is involved in a variety of neurological processes and diseases. L-kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.

トリプトファンの分解経路における重要な中間体です。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)