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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
whole antiserum
抗体製品タイプ
secondary antibodies
クローン
polyclonal
含みます
15 mM sodium azide
テクニック
indirect ELISA: 1:100,000
quantitative precipitin assay: 1.5 mg/mL
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
関連するカテゴリー
詳細
IgG contains four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, that are associated by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4.
アプリケーション
Anti-Human IgG (Fc specific) antibody produced in rabbit was used in immunoblotting and immunocytochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
生物化学的／生理学的作用
IgG activates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a pivotal role in antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis. It might be linked to allergy and has the longest serum half life.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
調製ノート
treated to remove lipoproteins
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
I9135-BULK:
I9135-VAR:
I9135-2ML:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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Nancy William et al.
Molecular psychiatry (2021-06-26)
Suicide is a significant public health concern with complex etiology. Although the genetic component of suicide is well established, the scope of gene networks and biological mechanisms underlying suicide has yet to be defined. Previously, we reported genome-wide evidence that
John D Bartlett et al.
Cells, tissues, organs, 194(2-4), 222-226 (2011-04-29)
Dental enamel development occurs in stages as observed by the changing morphology of the ameloblasts that are responsible for enamel formation. During the secretory stage of development, proteins including MMP20 are secreted into the enamel matrix. MMP20 is required for
Kimberly M Stroka et al.
Blood, 118(6), 1632-1640 (2011-06-10)
A vast amount of work has been dedicated to the effects of shear flow and cytokines on leukocyte transmigration. However, no studies have explored the effects of substrate stiffness on transmigration. Here, we investigated important aspects of endothelial cell contraction-mediated
Puja Gupta et al.
BMC biotechnology, 10, 72-72 (2010-10-12)
EGF receptor variant III (EGFRvIII) is the most common variant of the EGF receptor observed in human tumors. It results from the in frame deletion of exons 2-7 and the generation of a novel glycine residue at the junction of
Franco Klingberg et al.
The Journal of cell biology, 207(2), 283-297 (2014-10-22)
Integrin-mediated force application induces a conformational change in latent TGF-β1 that leads to the release of the active form of the growth factor from the extracellular matrix (ECM). Mechanical activation of TGF-β1 is currently understood as an acute process that
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