G1279

G 418 二硫酸塩

powder, suitable for plant cell culture, BioReagent

• 別名: 抗生物質 G418
• 実験式（ヒル表記法）: C₂₀H₄₀N₄O₁₀ · 2H₂SO₄
• CAS番号: 108321-42-2
• 分子量: 692.71
• MDL番号: MFCD00058314
• UNSPSCコード: 10171502
• PubChem Substance ID: 24895058
• NACRES: NA.72

特性

• product name: G 418 二硫酸塩, suitable for plant cell culture, BioReagent
• 製品種目: BioReagent
• 形状: powder
• 有効性: ≥720 μg per mg (Dried basis)
• テクニック: cell culture | plant: suitable
• 色: white to off-white
• 溶解性: 100 mg/mL (H₂O clear)
• 抗生物質活性スペクトル: Gram-negative bacteria
• アプリケーション: agriculture
• 作用機序: protein synthesis | interferes
• 保管温度: 2-8°C
• SMILES記法: OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O
• InChI: 1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1
• InChI Key: UHEPSJJJMTWUCP-NKCAIAFTSA-N

詳細

詳細

Chemical structure: aminoglycoside

アプリケーション

G418 disulfate salt is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells transfected with a iNOS promoter construct and neomycin resistance gene†. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 μg/mL or less while animal cells may require 300-500 μg/mL.

注意

The product is stable for three years when stored at 2-8°C.

調製ノート

G418 powder is soluble in water at 100 mg/mL.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H317,H334
• 注意書き: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• 危険有害性の分類: Resp. Sens. 1 - Skin Sens. 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)