G002

イソグバシン 塩酸塩

solid

• 別名: 1,2,3,6-テトラヒドロ-4-ピリジンカルボン酸 塩酸塩
• 実験式（ヒル表記法）: C₆H₉NO₂ · HCl
• CAS番号: 68547-97-7
• 分子量: 163.60
• MDL番号: MFCD00055192
• UNSPSCコード: 12352200
• PubChem Substance ID: 24278160
• NACRES: NA.77

特性

• 形状: solid
• 色: white
• 溶解性: H₂O: soluble (refrigerate if not used immediately.); methanol: slightly soluble; neutral and acidic solutions: stable (in basic solutions the free amine can oxidize easily)
• SMILES記法: Cl[H].OC(=O)C1=CCNCC1
• InChI: 1S/C6H9NO2.ClH/c8-6(9)5-1-3-7-4-2-5;/h1,7H,2-4H2,(H,8,9);1H
• InChI Key: SUWREQRNTXCCBL-UHFFFAOYSA-N
• 遺伝子情報: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562)

詳細

アプリケーション

Isoguvacine hydrochloride has been used as a γ-aminobutyric acid type A (GABA_A) receptor agonist:

• to study its effects on neuronal activity in rats
• to study its antiallodynic effect in rats
• to study its effects on baroreflex gains in rats

生物化学的／生理学的作用

Isoguvacine is a strong γ-aminobutyric acid A (GABA_A) receptor agonist.

特徴および利点

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves