F0287

フィブロネクチン 溶液 ヒト線維芽細胞由来

lyophilized powder, 70 kDa

• 別名: Fibronectin
• MDL番号: MFCD00131062
• UNSPSCコード: 12352202
• eCl@ss: 42020141
• NACRES: NA.75

特性

• 由来生物: human plasma
• 品質水準: 200
• アッセイ: >90% (SDS-PAGE)
• フォーム: lyophilized powder
• 分子量: 70 kDa
• 包装: pkg of 0.5 mg
• テクニック: cell culture | mammalian: suitable
• 不純物: HIV and HBsAg, source material tested negative; Small proteolytic fragments, may contain traces
• 溶解性: water: soluble ≥0.500 mg/mL, clear to slightly hazy, colorless
• UniProtアクセッション番号: P02751
• 輸送温度: ambient
• 保管温度: −20°C
• 遺伝子情報: human ... FN1(2335)

詳細

詳細

Fibronectin 1 is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. FN1 is mapped to human chromosome 2q35. Proteolytic fragments of fibronectin has a cell binding domain.

アプリケーション

Fibronectin Proteolytic Fragment from human plasma has been used in pre adsorbed antibody blocking assay and EC-pericyte tube coassembly.

生物化学的／生理学的作用

Fibronectin participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis. Proteolytic fragments of fibronectin plays a vital role in mononuclear phagocyte function.

注意

凍結乾燥品(PBS, 凍結保護剤としてスクロ-ス含有)

調製ノート

70 kDaのこのN末端断片は、カテプシンDの消化により得られます。

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable