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主要文書

EHU130111

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human CTCF

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About This Item

UNSPSCコード:

41105324

NACRES:

NA.51

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Sigma-Aldrich

SHCLNG

MISSION^® shRNA

SHRNA

MISSION^® shRNA Product Offerings

SIRNA

MISSION^® siRNA Product Offerings

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SHCLND

MISSION^® shRNA

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SHC002

MISSION^® pLKO.1-puro 非哺乳shRNAコントロールプラスミドDNA

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SIC001

MISSION^® siRNA Universal Negative Control #1

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SH3011

MISSION^® shRNAヒト遺伝子ファミリーセット、大腸菌グリセロールストック

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SHC002V

MISSION^® pLKO.1-puro Non-Mammalian shRNA Control Transduction Particles（MISSION pLKO.1-puro非哺乳類shRNAコントロール形質導入粒子）

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S1452

MISSION^® siRNAトランスフェクション試薬

Sigma-Aldrich

SHC016

MISSION^® pLKO.1-puro 非標的shRNAコントロールプラスミドDNA

詳細

製品種目

MISSION^®

フォーム

lyophilized powder

esiRNA cDNA標的配列

AACAGCAGGAGGGTCTGCTATCAGAGGTTAATGCAGAGAAAGTGGTTGGTAATATGAAGCCTCCAAAGCCAACAAAAATTAAAAAGAAAGGTGTAAAGAAGACATTCCAGTGTGAGCTTTGCAGTTACACGTGTCCACGGCGTTCAAATTTGGATCGTCACATGAAAAGCCACACTGATGAGAGACCACACAAGTGCCATCTCTGTGGCAGGGCATTCAGAACAGTCACCCTCCTGAGGAATCACCTTAACACACACACAGGTACTCGTCCTCACAAGTGCCCAGACTGCGACATGGCCTTTGTGACCAGTGGAGAATTGGTTCGGCATCGTCGTTACAAACACACCCACGAGAAGCCATTCAAGTGTTCCATGTGCGATTACGCCAGTGTAGAAGTCAGCAAATTAAAACGTCACATTCGCTCTCATACTGGAGAGCGTCCGTTTCAGTGCAGTTTGTGCAGTTATGCCAGCAGGGACACATACAAGCTGAAAAGGCACATGA

Ensembl |ヒトアクセッション番号

ENSG00000102974

NCBIアクセッション番号

NM_006565

輸送温度

ambient

保管温度

−20°C

遺伝子情報

human ... CTCF(10664) , CTCF(10664)

詳細

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法的情報

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

10 - Combustible liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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CTCF regulates the FoxO signaling pathway to affect the progression of prostate cancer.

Zhengfei Shan et al.

Journal of cellular and molecular medicine, 23(5), 3130-3139 (2019-03-16)

The present research focuses on the influence of CCCTC-binding factor (CTCF) on prostate cancer (PC) via the regulation of the FoxO signalling pathway. A bioinformatics analysis was conducted to screen out target genes for CTCF in LNCaP cells and to

CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions.

Elisa Fiorito et al.

Nucleic acids research, 44(22), 10588-10602 (2016-09-18)

Enhancer regions and transcription start sites of estrogen-target regulated genes are connected by means of Estrogen Receptor long-range chromatin interactions. Yet, the complete molecular mechanisms controlling the transcriptional output of engaged enhancers and subsequent activation of coding genes remain elusive.

PAtCh-Cap: input strategy for improving analysis of ChIP-exo data sets and beyond.

Tommy W Terooatea et al.

Nucleic acids research, 44(21), e159-e159 (2016-08-24)

Recently, a number of advances have been implemented into the core ChIP-seq (chromatin immunoprecipitation coupled with next-generation sequencing) methodology to streamline the process, reduce costs or improve data resolution. Several of these emerging ChIP-based methods perform additional chemical steps on

CTCF loss mediates unique DNA hypermethylation landscapes in human cancers.

Nathan A Damaschke et al.

Clinical epigenetics, 12(1), 80-80 (2020-06-07)

The chromatin insulator CCCTC-binding factor (CTCF) displays tissue-specific DNA binding sites that regulate transcription and chromatin organization. Despite evidence linking CTCF to the protection of epigenetic states through barrier insulation, the impact of CTCF loss on genome-wide DNA methylation sites

CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication.

Francisco Puerta Martínez et al.

Journal of virology, 88(13), 7389-7401 (2014-04-18)

Human cytomegalovirus (HCMV) gene expression during infection is highly regulated, with sequential expression of immediate-early (IE), early (E), and late (L) gene transcripts. To explore the potential role of chromatin regulatory factors that may regulate HCMV gene expression and DNA

主要文書

MISSION^® esiRNA