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About This Item
化学式:
C14H20NO11Na
CAS番号:
分子量:
401.30
MDL番号:
UNSPSCコード:
12352201
PubChem Substance ID:
NACRES:
NA.25
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品質水準
アッセイ
≥95% (HPLC)
フォーム
powder
色
white
溶解性
H2O: soluble 10 mg/mL, clear, colorless
保管温度
−20°C
SMILES記法
[Na].CC(=O)NC(C=O)C(OC1OC(=CC(O)C1O)C(O)=O)C(O)C(O)CO
InChI
1S/C14H21NO11.Na.H/c1-5(18)15-6(3-16)12(10(21)8(20)4-17)26-14-11(22)7(19)2-9(25-14)13(23)24;;/h2-3,6-8,10-12,14,17,19-22H,4H2,1H3,(H,15,18)(H,23,24);;
InChI Key
SDRQEYWJTBWGNE-UHFFFAOYSA-N
詳細
Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.
アプリケーション
Chondroitin disaccharide Δdi-0S may be used as a substrate for the identification and characterization of enzymes such as Clostridium perfringens unsaturated glucuronyl hydrolase. Chondroitin disaccharide Δdi-0S may be used as a reference compound in the analysis of chondroitin disaccharide sulfates.
その他情報
ΔUA = 4-deoxy-L-threo-hex-4-enopyranosyluronic acid; GalNAc = N-acetyl-D-galactosamine
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
C3920-VAR:
C3920-10MG:
C3920-BULK:
C3920-5MG:
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Yusuke Nakamichi et al.
The Journal of biological chemistry, 286(8), 6262-6271 (2010-12-15)
Pathogenic Streptococcus agalactiae produces polysaccharide lyases and unsaturated glucuronyl hydrolase (UGL), which are prerequisite for complete degradation of mammalian extracellular matrices, including glycosaminoglycans such as chondroitin and hyaluronan. Unlike the Bacillus enzyme, streptococcal UGLs prefer sulfated glycosaminoglycans. Here, we show
Glucosamine and chondroitin sulfate.
Miller KL, Clegg DO.
Rheumatic Diseases Clinics of North America, 23(1), 103-118 (2011)
The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system.
Galtrey CM, Fawcett JW.
Brain Research. Brain Research Reviews, 54, 1-18 (2007)
Kemal Solakyildirim et al.
Analytical biochemistry, 397(1), 24-28 (2009-09-23)
Chondroitin sulfate (CS) has an important role in cell division, in the central nervous system, and in joint-related pathologies such as osteoarthritis. Due to the complex chemical structure and biological importance of CS, simple, sensitive, high resolution, and robust analytical
J C F Kwok et al.
The international journal of biochemistry & cell biology, 44(4), 582-586 (2012-01-24)
Chondroitin sulfate is a glycosaminoglycan composed of N-acetylgalactosamine and glucuronic acid. It attaches to a core protein to form chondroitin sulfate proteoglycan (CSPG). Being a major component of the brain extracellular matrix, CSPGs are involved in neural development, axon pathfinding
資料
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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