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詳細
Aflatoxin B1 is the most abundant and significant member of the group, which includes B2, B2a, G1, G2a, M1, M2, P1, Q1, aflatoxicol I (natural isomer), aflatoxicol II (unnatural isomer), tetrahydrodeoxy aflatoxin B1, and the unstable reactive B1 (8,9)-epoxide.
Aflatoxins are highly carcinogenic.
Aflatoxins are highly toxic mycotoxins produced by the fungus Aspergillus. Aflatoxins are commonly found in various grains and peanut butter.
Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins.
The antibody reacts with the B1 aflatoxin and also recognizes aflatoxins G1, B2, and the KLH protein. No cross-reaction is observed with aflatoxins and B2a, G2, G2a, M1.
特異性
Sensitivity range for this product is 0.005-20 ng/ml of aflatoxin B1.
免疫原
aflatoxin B1-KLH.
アプリケーション
Rabbit Anti-Aflatoxin B1 antibody has been used for the development of electrochemical immunosensors. The antibody has also been used in designing novel sandwich immunoassays. The product can also be used for capture ELISA at a dilution of 1:1,000.
生物化学的/生理学的作用
Aflatoxin B1 and its metabolites act as potent carcinogens, mutagens and teratogens. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry.
物理的形状
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
A8679-BULK:
A8679-.5ML:
A8679-1ML:
A8679-.5ML-PW:
A8679-VAR:
A8679-1ML-PW:
試験成績書(COA)
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Analytical and bioanalytical chemistry, 388(5-6), 1069-1074 (2007-06-15)
Aflatoxins are a group of mycotoxins that have deleterious effects on humans and are produced during fungal infection of plants or plant products. An electrochemical immunosensor for the determination of aflatoxin B(1) (AFB(1)) was developed with AFB(1)antibody (AFB(1)-Ab) immobilized on
Neuroscience letters, 111(3), 344-350 (1990-04-06)
The effects of calcitonin gene-related peptide (CGRP) on synaptic mechanisms were studied at the frog neuromuscular junction by using classical electrophysiological techniques. CGRP reduced the quantal content of evoked neurotransmitter release, as well as the sensitivity of postsynaptic nicotinic acetylcholine
An over review on effect of aflatoxin in animal husbandry
Asian journal of experimental biological sciences, 2(3), 754-757 (2011)
Sensors (Basel, Switzerland), 18(2) (2018-02-22)
Aflatoxins (AFs) are highly toxic compounds that can cause both acute and chronic toxicity in humans. Aflatoxin B1 (AFB1) is considered the most toxic of AFs. Therefore, the rapid and on-site detection of AFB1 is critical for food safety management.
International journal of food microbiology, 135(1), 47-52 (2009-08-18)
The enzymatic degradation of aflatoxin B(1) (AFB(1)) by white rot fungi through laccase production was investigated in different liquid media. A significant (P<0.0001) correlation was observed between laccase activity and AFB(1) degradation exhibited by representatives of Peniophora and Pleurotus ostreatus
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