A7219

L-アスパラギン酸

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

• 別名: (S)-(+)-アミノコハク酸, (S)-アミノブタン二酸
• 化学式: HO₂CCH₂CH(NH₂)CO₂H
• CAS番号: 56-84-8
• 分子量: 133.10
• Beilstein: 1723530
• EC Number: 200-291-6
• MDL番号: MFCD00002616
• UNSPSCコード: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24891191
• NACRES: NA.75

特性

• 由来生物: non-animal source
• 品質水準: 300
• 認証: meets EP testing specifications; meets USP testing specifications
• アッセイ: 98.5-101.0%
• フォーム: powder
• テクニック: cell culture | mammalian: suitable
• 不純物: endotoxin, tested
• 色: white to off-white
• mp: >300 °C (dec.) (lit.)
• 溶解性: 1 M HCl: 100 mg/mL
• SMILES記法: N[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
• InChI Key: CKLJMWTZIZZHCS-REOHCLBHSA-N
• 遺伝子情報: human ... CA1(759) , CA2(760) ; rat ... Grin2a(24409)

詳細

詳細

Aspartic acid(ASP)/aspartate, a non-essential amino acid, is naturally produced by mammals. ASP is one of the 20 building-block amino acids of proteins and has a one letter code, D. L-Aspartic acid can be manufactured industrially by an enzymatic process using the aspartase enzyme.

アプリケーション

L-Aspartic acid has been used:

• as an aspartame (ASP) metabolite to determine acetylcholinesterase (AChE) activity in the hippocampal homogenate of suckling rats
• as printed chemotaxis ligands to screen chemotaxis receptors with high-throughput technologies and verify the interactions with surface plasmon resonance (SPR) and nuclear magnetic resonance (NMR)
• as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) for supplementation assays of various cultured cell lines

生物化学的／生理学的作用

速いシナプス興奮を伝える主要な神経伝達物質です。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves