A6979

抗AtMPK4抗体 ウサギ宿主抗体

affinity isolated antibody, liquid

• 別名: 抗シロイヌナズナMPK4抗体
• MDL番号: MFCD07370260
• UNSPSCコード: 12352203
• NACRES: NA.44

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• グレード: for molecular biology
• クローン: polyclonal
• 形状: liquid
• 分子量: antigen 43 kDa
• 化学種の反応性: Arabidopsis thaliana
• テクニック: western blot: 0.5-1 μg/mL using extract (cytosolic fraction) of Arabidopsis thaliana and Nicotiana tabacum leaves
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: Arabidopsis thaliana ... ATMPK4(828151)

詳細

詳細

Anti-AtMPK4 is produced in rabbit using as immunogen a synthetic peptide corresponding to the C-terminus of Arabidopsis thaliana MPK4 (Anti- mitogen-activated protein kinase-4), conjugated to KLH. In Arabidopsis thaliana, 20 genes (MPKs) encode putative plant MAPKs, which can be grouped into four or five classes according to sequence similarity. All plant mitogen-activated protein kinase (MAPKs) are classified into the plant extracellular-regulated kinase (PERK) subfamily.

Mitogen-activated protein kinase-4 (MPK4) is expressed in the nucleus. In pre-mitotic and interphase cells, it is found in the cytoplasm.

免疫原

シロイヌナズナArabidopsis thalianaMPK4のC-末端(アミノ酸365-376)に対応する合成ペプチド。この配列は、AtMPK4に特異的で、他の20の既知AtMPKアイソフォ-ムにはみられません。AtMPK5・AtMPK12アイソフォ-ムとは50-60%一致(連続エピト-プ)です。

アプリケーション

Anti- mitogen-activated protein kinase-4 (AtMPK4) antibody produced in rabbit has been used for Western blotting.

Anti-AtMPK4 antibody has been used in

• immunoblotting
• immunoprecipitation
• co-immunoprecipitation
• western blotting

生物化学的／生理学的作用

In Arabidopsis thaliana putative functions have been assigned to AtMPK3, AtMPK4, and AtMPK6, and all three mitogen-activated protein kinase (MAPKs) have been linked to diverse stress responses, including oxidative stress signaling, pathogen defense, drought, high salt, cold, and touch. Arabidopsis MAPKs, Anti- mitogen-activated protein kinase-3 (AtMPK3), Anti- mitogen-activated protein kinase-4 (AtMPK4), and Anti- mitogen-activated protein kinase-6 (AtMPK6) are rapidly and transiently activated by stress responses, by activation of distinct signal transduction pathways, involving upstream MAPKKKs (e.g. AtANP1 and AtMEKK1) and MAPKKs including AtMKK1/2 and AtMKK4/5.

Mitogen-activated protein kinase-4 (MPK4) negatively modulates systemic-acquired resistance. It functions as a regulator of retrograde signaling for photosynthesis, growth and immune defenses. It also has a role in cytokinesis and microtubule organization.

物理的形状

0.01M PBS溶液(pH 7.4, 15mMアジ化ナトリウム含有)

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable