A5855

Abz-LFK(Dnp)-OH トリフルオロアセタート塩

≥97% (HPLC)

• 別名: O-Aminobenzoic acid-Leu-Phe-Lys(DNP)-OH トリフルオロアセタート塩
• 実験式（ヒル表記法）: C₃₄H₄₁N₇O₉ · xC₂HF₃O₂
• 分子量: 691.73 (free base basis)
• MDL番号: MFCD11045275
• UNSPSCコード: 12352200
• PubChem Substance ID: 329770877
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥97% (HPLC)
• 形状: film
• 色: yellow
• 保管温度: 2-8°C
• SMILES記法: OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)c1ccccc1N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCCNc3ccc(cc3[N+]([O-])=O)[N+]([O-])=O)C(O)=O
• InChI: 1S/C34H41N7O9.C2HF3O2/c1-21(2)18-28(38-31(42)24-12-6-7-13-25(24)35)32(43)39-29(19-22-10-4-3-5-11-22)33(44)37-27(34(45)46)14-8-9-17-36-26-16-15-23(40(47)48)20-30(26)41(49)50;3-2(4,5)1(6)7/h3-7,10-13,15-16,20-21,27-29,36H,8-9,14,17-19,35H2,1-2H3,(H,37,44)(H,38,42)(H,39,43)(H,45,46);(H,6,7)/t27-,28-,29-;/m0./s1
• InChI Key: BAXBDLHYKKDHEJ-BJRQXHFHSA-N

詳細

Amino Acid Sequence

Abz-Leu-Phe-Lys-DNP

アプリケーション

Abz-LFK(Dnp)-OH trifluoroacetate (TFA) salt is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate that binds specifically to the C domain of ACE. Abz-LFK(Dnp)-OH TFA has been used to study the development of new antibacterial calixarene derivatives, as well as the efficacy and toxicity of the antimicrobial peptide M33 as a possible antimicrobial agent in lung infections and sepsis.

生物化学的／生理学的作用

Abz-LFK(Dnp)-OH is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate specific for the C domain for real time fluorescent assay (ACE, Peptidyl Dipeptidase, Kininase II, E.C. 3.4.15.1).

特徴および利点

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable