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About This Item
実験式（ヒル表記法）:
C14H4N2Na2O8
CAS番号:
分子量:
374.17
MDL番号:
UNSPSCコード:
12352005
PubChem Substance ID:
NACRES:
NA.79
おすすめの製品
由来生物
fermentation/recombinant
品質水準
アッセイ
≥97.0% (HPLC)
フォーム
powder
色
red-brown to deep orange
red-brown to deep red-brown
保管温度
2-8°C
SMILES記法
OC(=O)c1cc(nc2C(=O)C(=O)c3cc([nH]c3-c12)C(=O)O[Na])C(=O)O[Na]
InChI
1S/C14H6N2O8.2Na/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;/q;2*+1/p-2
InChI Key
UFVBOGYDCJNLPM-UHFFFAOYSA-L
詳細
Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.
アプリケーション
- Safety assessment of a novel, dietary pyrroloquinoline quinone disodium salt (mnemoPQQ): This study investigates the safety profile of Methoxatin disodium salt, which has implications for its application in assay development for clinical and diagnostic purposes. Specifically, it addresses the compound′s use in dietary supplements and potential crossover into clinical assays where safety and toxicity are paramount (Shiojima et al., 2022).
生物化学的／生理学的作用
In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
80198-VAR-F:
80198-50MG-F:
80198-10MG-F:
80198:
80198-BULK-F:
Chee-Hoe Ng et al.
Neurobiology of aging, 55, 33-37 (2017-04-14)
Despite intensive research, the etiology of Parkinson's disease (PD) remains poorly understood and the disease remains incurable. However, compelling evidence gathered over decades of research strongly support a role for mitochondrial dysfunction in PD pathogenesis. Related to this, PGC-1α, a
Xing-Qin Zhou et al.
Scientific reports, 8(1), 8894-8894 (2018-06-13)
Oxidative stress is known to be associated with various age-related diseases. D-galactose (D-gal) has been considered a senescent model which induces oxidative stress response resulting in memory dysfunction. Pyrroloquinoline quinone (PQQ) is a redox cofactor which is found in various
Evidence for methoxatin (pyrroloquinolinequinone) as the cofactor in bovine plasma amine oxidase from resonance Raman spectroscopy
Moog RS, et al.
Proceedings of the National Academy of Sciences of the USA, 83(22), 8435-8439 (1986)
Gerasimos F Kremmydas et al.
PloS one, 8(4), e61808-e61808 (2013-04-19)
Pseudomonas fluorescens strain X, a bacterial isolate from the rhizosphere of bean seedlings, has the ability to suppress damping-off caused by the oomycete Pythium ultimum. To determine the genes controlling the biocontrol activity of strain X, transposon mutagenesis, sequencing and
Vitamins
Clinical biochemistry of domestic animals, 695-730 (2008)
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