76546

Lipase, immobilized on Immobead 150 Thermomyces lanuginosus由来

≥3000 U/g

• 別名: Immobilized lipase, Lipase enzyme
• UNSPSCコード: 12352204
• NACRES: NA.54

特性

• 由来生物: fungus (Thermomyces lanuginosus)
• 品質水準: 100
• 形状: powder (or beads)
• 比活性: ≥3000 U/g
• テクニック: analytical sample preparation: suitable
• 色: white to off-white
• アプリケーション: life science and biopharma
• 保管温度: 2-8°C

詳細

詳細

Research area: Cell Signaling

Lipase from Thermomyces lanuginosus (TLL) is a basophilic, single-chain protein and thermostable enzyme. It belongs to the alpha/beta-hydrolase fold family. TLL is roughly spherical and is made up of a central seven-stranded β-parallel sheet with five interconnecting α-helices.

アプリケーション

Lipase, immobilized on Immobead 150 from Thermomyces lanuginosus has been used:

• as a biocatalyst to study ultrasound-assisted transesterification of a blend of non-edible oils with methanol.
• as a catalyst in the synthesis of medium chain fatty acids (MCFA) and polyunsaturated fatty acids (PUFA) rich oils by enzymatic structuring of flax seed oil.
• for the resolution of chiral compounds and the transesterification production of biodiesel.
• to enhance the efficiency and selectivity of the enzymatic synthesis of ethyl-(R)-2-hydroxy-4-phenylbutyrate, (R)-HPB ester.
• to facilitate a chemoenzymatic process for the continuous synthesis of (S)-7-((tert-Butyldiphenylsilyl)oxy)hept-1-yn-4-ol, a crucial intermediate for Eribulin synthesis, within a packed-bed reactor setup.

生物化学的／生理学的作用

リパーゼは、トリアシルグリセロールの加水分解を触媒して、グリセロールおよび遊離脂肪酸を生成します。

It participates in catalyzing the hydrolysis of triglycerides at the water-lipid interface and produces mono-, di-glycerides, and free fatty acids. Due to its versatility, this enzyme is applicable in various industries including, detergents, paper, leather, baking, fine chemicals, fuel, and biocatalysts.

単位の定義

1 Uは、トリブチリン(製品番号91010)を基質として、pH 7.5、40°C、1分間に、1 μmolの酪酸を遊離させる酵素量に相当します。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)