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由来生物
mouse
品質水準
100
500
結合体
unconjugated
抗体製品の状態
culture supernatant
抗体製品タイプ
primary antibodies
クローン
GS-6, monoclonal
詳細
For In Vitro Diagnostic Use in Select Regions (See Chart)
フォーム
buffered aqueous solution
化学種の反応性
human
包装
vial of 0.1 mL concentrate (389M-14)
vial of 0.5 mL concentrate (389M-15)
bottle of 1.0 mL predilute (389M-17)
vial of 1.0 mL concentrate (389M-16)
bottle of 7.0 mL predilute (389M-18)
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
アイソタイプ
IgG2a
コントロール
hepatocellular carcinoma
輸送温度
wet ice
保管温度
2-8°C
視覚化
cytoplasmic
遺伝子情報
human ... GLUL(2752)
詳細
Glutamine synthetase (GS) catalyzes the synthesis of glutamine from glutamate and ammonia in the mammalian liver. In normal liver, GS expression is seen in centrilobular (zone 3) hepatocytes, but not in mid-zone (zone 2) or periportal (zone 3) hepatocytes. Glutamine synthetase immunohistochemistry is also positive in neoplasms of hepatocyte origin, such as hepatocellular carcinoma (HCC) and hepatocellular adenoma, making it useful for identifying these tumors.
品質
![]() IVD | ![]() IVD | ![]() IVD | ![]() RUO |
関連事項
Glutamine Synthetase Positive Control Slides, Product No. 389S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
物理的形状
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
調製ノート
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
その他情報
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
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試験成績書(COA)
Lot/Batch Number
Luca Di Tommaso et al.
Hepatology (Baltimore, Md.), 45(3), 725-734 (2007-02-28)
Hepatocellular nodules in cirrhosis include regenerative (large regenerative, LRN) and dysplastic (low and high grade, LGDN and HGDN) nodules, early and grade 1 HCC (eHCC-G1), and overt HCC. The differential diagnosis may be particularly difficult when lesions such as HGDN
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