05129

L-アラニン

BioUltra, ≥99.5% (NT)

• 別名: (S)-2-アミノプロピオン酸, L-α-アミノプロピオン酸
• 実験式（ヒル表記法）: C₃H₇NO₂
• CAS番号: 56-41-7
• 分子量: 89.09
• Beilstein: 1720248
• EC Number: 200-273-8
• MDL番号: MFCD00064410
• UNSPSCコード: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 329747639
• NACRES: NA.26

特性

• 製品種目: BioUltra
• アッセイ: ≥99.5% (NT)
• 形状: powder or crystals
• 光学活性: [α]20/D +14.0±1.0°, c = 5% in 5 M HCl
• 不純物: insoluble matter, passes filter test; ≤0.3% foreign amino acids
• 強熱残分: ≤0.05%
• 損失: ≤0.05% loss on drying, 20 °C (HV)
• 色: colorless to white
• pH: 5.5-7.0 (25 °C, 1 M in H₂O)
• mp: 314.5 °C
• 溶解性: H₂O: 1 M at 20 °C, clear, colorless
• 微量陰イオン: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• 微量陽イオン: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤100 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• UV吸収: λ: 260 nm A_max: ≤0.03; λ: 280 nm A_max: ≤0.02
• アプリケーション: detection
• SMILES記法: C[C@H](N)C(O)=O
• InChI: 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
• InChI Key: QNAYBMKLOCPYGJ-REOHCLBHSA-N
• 遺伝子情報: human ... CA1(759) , CA2(760)

詳細

アプリケーション

• A Color Indicator Based on 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide (MTT) and a Biodegradable Poly(ester amide) for Detecting Bacterial Contamination.: This study developed a biodegradable poly(ester amide) containing L-Alanine used with MTT for the detection of bacterial contamination, highlighting its potential in health-related applications (Franco et al., 2024).


• Randomized Trial to Assess the Safety and Tolerability of Daily Intake of an Allulose Amino Acid-Based Hydration Beverage in Men and Women.: Investigates the impact of a daily hydration beverage supplemented with L-Alanine among other amino acids on hydration and nutrient uptake in humans, emphasizing its safety and efficacy (Bloomer et al., 2024).


• Comparison of methods for the NMR measurement of motionally averaged dipolar couplings.: This study utilizes L-Alanine samples to compare NMR methods for measuring dipolar couplings, contributing to the improvement of NMR spectroscopy techniques (Southern et al., 2024).

生物化学的／生理学的作用

Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and α-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system. Increased alanine levels correlate with higher blood pressure, energy intake, cholesterol levels, and body mass index.

その他情報

タンパク質に対して塩溶効果を示すと考えられています。各種微生物の増殖に必要とされる物質です。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)