571261

ピペリジン

biotech. grade, ≥99.5%

• 別名: ヘキサヒドロピリジン
• 実験式（ヒル表記法）: C₅H₁₁N
• CAS番号: 110-89-4
• 分子量: 85.15
• Beilstein: 102438
• EC Number: 203-813-0
• MDL番号: MFCD00005979
• UNSPSCコード: 12352005
• PubChem Substance ID: 329758271
• NACRES: NA.21
• bp: 106 °C (lit.); 106 °C

特性

• グレード: biotech. grade
• 蒸気密度: 3 (vs air)
• 蒸気圧: 23 mmHg ( 20 °C)
• アッセイ: ≥99.5%
• フォーム: liquid
• テクニック: DNA sequencing: suitable
• 不純物: <0.3% water
• 屈折率: n20/D 1.452 (lit.)
• bp: 106 °C (lit.); 106 °C
• mp: −13 °C (lit.)
• 溶解性: organic solvents: soluble(lit.); water: miscible(lit.)
• 密度: 0.862 g/mL at 20 °C (lit.)
• λ: 1 cm path, H₂O reference
• UV吸収: λ: 290 A_max: <1.000; λ: 370 A_max: <0.050
• SMILES記法: C1CCNCC1
• InChI: 1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2
• InChI Key: NQRYJNQNLNOLGT-UHFFFAOYSA-N

詳細

詳細

Piperidine, a heterocyclic cyclohexane is a volatile secondary amine. Maxam-Gilbert chemical method, a DNA sequencing technology employs piperidine to rupture DNA strands at damaged base site. Its crystal structure analyzed at 150K shows hydrogen bonding between NH groups. Piperidine ring forms a part of many naturally occuring alkaloids. It is prepared on an industrial scale by the hydrogenation of pyridine in the presence of nickel catalyst. The ¹H NMR spectrum of piperidine has been recorded.

アプリケーション

Applied Biosystem社製 431型及び433A型　ペプチドシンセサイザに適合。

Piperidine has been used in combination with DMF (dimethylformamide) for the removal of Fmoc (fluorenylmethyloxycarbonyl) group from the N-terminal amino group during peptide synthesis.

安全性情報

• ピクトグラム: GHS02,GHS06,GHS05
• シグナルワード: Danger
• 危険有害性情報: H225,H302,H311 + H331,H314
• 注意書き: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 60.8 °F - closed cup
• 引火点(℃): 16 °C - closed cup