PHR3195

レボセチリジン 二塩酸塩

pharmaceutical secondary standard, certified reference material

• 別名: (-)-セチリジン 二塩酸塩; 2-[2-[4-[(R)-(4-クロロフェニル)-フェニル-メチル]ピペラジン-1-イル]エトキシ]酢酸 二塩酸塩
• 実験式（ヒル表記法）: C₂₁H₂₅ClN₂O₃·2HCl
• CAS番号: 130018-87-0
• 分子量: 461.81
• MDL番号: MFCD07366507
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to USP 1359969
• APIファミリー: cetirizine
• CofA: current certificate can be downloaded
• 包装: pkg of 500 mg
• アプリケーション: pharmaceutical
• 保管温度: 2-8°C
• SMILES記法: Cl.Cl.OC(=O)COCCN1CCN(CC1)[C@H](c2ccccc2)c3ccc(Cl)cc3
• InChI: 1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/m1../s1
• InChI Key: PGLIUCLTXOYQMV-GHVWMZMZSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

アプリケーション

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

レボセチリジン塩酸塩は、非鎮静型抗ヒスタミン薬です。ヒスタミンH1受容体拮抗薬であり、セチリジンの活性型アイソマーです。レボセチリジンは、生物学的利用能が高く、H1受容体に対して高い親和性、高い占有率を示します。

アナリシスノート

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302,H400
• 注意書き: P264 - P270 - P273 - P301 + P312 - P391 - P501
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Acute 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable