PHR1397

フルオシノロンアセトニド

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: 6α,9α-ジフルオロ-11β,16α,17α,21-テトラヒドロキシ-1,4-プレグナジエン-3,20-ジオン, 6α,9α-ジフルオロ-16α-ヒドロキシプレドニゾロン 16,17-アセトニド, 6α-フルオロトリアミシノロンアセトニド, Sinalar, Synandone
• 実験式（ヒル表記法）: C₂₄H₃₀F₂O₆
• CAS番号: 67-73-2
• 分子量: 452.49
• EC Number: 200-668-5
• MDL番号: MFCD00010525
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823371
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to BP 160; traceable to Ph. Eur. F0200000; traceable to USP 1275009
• APIファミリー: fluocinolone
• CofA: current certificate can be downloaded
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 267-269 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
• InChI: 1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
• InChI Key: FEBLZLNTKCEFIT-VSXGLTOVSA-N
• 遺伝子情報: human ... NR3C1(2908)

詳細

詳細

Fluocinolone Acetonide is a soluble potent steroid, approved for implantable corticosteroid devices named fluocinolone acetonide intravitreal implants for the treatment of chronic uveitis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

Fluocinolone Acetonide may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using differential-pulse polarography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA2173 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable