グレード
analytical standard
品質水準
アッセイ
≥98.0% (TLC)
形状
powder
テクニック
HPLC: suitable
色
white to yellow
アプリケーション
forensics and toxicology
pharmaceutical (small molecule)
フォーマット
neat
SMILES記法
Cl.CNCC\C=C1/c2ccccc2COc3ccccc13
InChI
1S/C18H19NO.ClH/c1-19-12-6-10-16-15-8-3-2-7-14(15)13-20-18-11-5-4-9-17(16)18;/h2-5,7-11,19H,6,12-13H2,1H3;1H/b16-10+;
InChI Key
GNPPEZGJRSOKRE-QFHYWFJHSA-N
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アプリケーション
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
生物化学的／生理学的作用
ドキセピン代謝物。
特徴および利点
パウダーの有効期間は少なくとも10年間です。
その他情報
cis-異性体とtrans-異性体の混合物です。
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
N0392-25MG:
N0392-10MG:
N0392-BULK:
N0392-25MG-PW:
N0392-VAR:
Choose from one of the most recent versions:
C W Harrell et al.
Electrophoresis, 19(5), 712-718 (1998-06-18)
The separation of seven structurally similar antidepressant drugs (amitriptyline, nortriptyline, imipramine, desipramine, protriptyline, doxepin, and nordoxepin) was achieved in under 15 min using a novel nonionic micelle polymer, poly(n-undecyl-alpha-D-glucopyranoside) (PUG) by use of capillary zone electrophoresis (CZE). Systematic studies with
Robert Schomburg et al.
Journal of neural transmission (Vienna, Austria : 1996), 118(4), 641-645 (2011-02-26)
Doxepin--like other antidepressant drugs (ADs)--shows a variable antidepressant effect in clinical practice. The cause for this variability is as yet unclear; however, pharmacokinetic factors such as the variable permeability of doxepin into the cerebrospinal fluid (CSF), may contribute to the
K K Midha et al.
European journal of clinical pharmacology, 42(5), 539-544 (1992-01-01)
Commercial preparations of the tricyclic anti-depressant doxepin contain 15% of the more active cis-doxepin and 85% of the trans-isomer. The single dose pharmacokinetics of doxepin and its major metabolite N-desmethyldoxepin were examined in 30 healthy young men. Results for total
Heinz-Werner Hagedorn et al.
Journal of pharmaceutical and biomedical analysis, 29(1-2), 317-323 (2002-06-14)
Due to its tranquilizing properties, the tricyclic antidepressant doxepin may be misused as a doping agent in competition horses. Therefore, efficient analytical procedures are required to detect this drug in samples submitted for doping control. To screen for parent doxepin
M Meyer-Barner et al.
European journal of clinical pharmacology, 58(4), 253-257 (2002-07-24)
Little information on the population pharmacokinetics of the tricyclic antidepressant doxepine and its pharmacologically active metabolite desmethyldoxepine is available. However, a more individualised drug therapy may be feasible if the influence of various patient characteristics on plasma concentration was known.
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