すべての画像(1)
About This Item
実験式（ヒル表記法）:
C11H14N4O2
CAS番号:
分子量:
234.25
EC Number:
MDL番号:
UNSPSCコード:
41116107
PubChem Substance ID:
NACRES:
NA.24
おすすめの製品
![4-(DIMETHYLAMINO)BENZALDEHYDE [4-(DIMETHYLAMINO)BENZYLIDENE]HYDRAZONE AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/268/291/5232c253-7dd7-435c-b094-6d334239d9fb/640/5232c253-7dd7-435c-b094-6d334239d9fb.png)
グレード
analytical standard
品質水準
テクニック
HPLC: suitable
gas chromatography (GC): suitable
アプリケーション
forensics and toxicology
pharmaceutical (small molecule)
veterinary
フォーマット
neat
保管温度
2-8°C
SMILES記法
CC1=NC(N2C(OC)=CC(C)=N2)=NC(OC)=C1
InChI
1S/C11H14N4O2/c1-7-5-9(16-3)13-11(12-7)15-10(17-4)6-8(2)14-15/h5-6H,1-4H3
InChI Key
RHAXSHUQNIEUEY-UHFFFAOYSA-N
詳細
Mepirizole belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs), widely used in the treatment of pain and inflammation.
アプリケーション
Mepirizole may be used as an analytical reference standard for the quantification of the analyte in animal samples using ultra-high-performance liquid chromatography with tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
シグナルワード
Warning
危険有害性の分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
ターゲットの組織
Respiratory system
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
M9017-5G:
M9017-1G:
M9017-BULK:
M9017-VAR:
M9017-10G:
最新バージョンのいずれかを選択してください：
H Sekiguchi et al.
Arzneimittel-Forschung, 43(2), 134-138 (1993-02-01)
The effects of KU-1257 (N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea, CAS 120958-90-9) on gastric lesions and duodenal ulcers in rats were compared with those of various antiulcer drugs. KU-1257 prevented the formation of gastric lesions induced by necrotizing agents. The ID50 values against 0.6 N
Emilio Escrivà et al.
Inorganic chemistry, 42(25), 8328-8336 (2003-12-09)
A novel mu-pyrazolato-mu-hydroxo-dibridged copper(II) complex has been synthesized and structurally characterized: [(Cu(mepirizole)Br)2(mu-OH)(mu-pz)] (mepirizole=4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methylpyrimidine; pz=pyrazolate). The title compound crystallizes in the monoclinic system, space group P2(1)/c, with a=15.618(2) A, b=15.369(3) A, c=16.071(3) A, and beta=112.250(1) degrees. The structure is built up
K Terashima et al.
Chemical & pharmaceutical bulletin, 43(11), 2021-2023 (1995-11-01)
With a view to finding more effective antiulcer agents, a series of 2-benzylthio-5,6,7,8-tetrahydro-4(3H)-quinazolinones and related compounds were synthesized and evaluated in a histamine-stimulated gastric secretion model. The sodium salt of the 2-(dimethylamino)benzylthio derivative (8) showed gastric mucosal protection and gastric
K Ueshima et al.
Digestive diseases and sciences, 39(8), 1625-1632 (1994-08-01)
The role of body temperature in the acid stimulatory mechanism by mepirizole, a duodenal ulcerogen, was investigated in urethane-anesthetized rats. Subcutaneous administration of mepirizole (60 and 200 mg/kg) increased acid secretion in a dose-dependent manner and resulted in duodenal lesions
K Amagase et al.
Arzneimittel-Forschung, 46(2), 177-184 (1996-02-01)
The effects of (+/-)-(E)-1-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3-[2- [[[5-(methylamino)methyl-2-furyl] methyl]thio]ethyl]-2-(methylsulfonyl)guanidine (CAS 140695-21-2, T-593), a new histamine H2-receptor antagonist, on gastric secretion and experimental gastric and duodenal lesion/ulcer models in rats were examined. The drug administered orally or intraduodenally significantly and dose-dependently inhibited both basal
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）