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ligand
quaternary amine
品質水準
詳細
Natrix® Q Process 150
製品種目
Natrix®
パラメーター
0.6-3 L/min flow rate
ベッド高
0.5 mm
ベッド容積
115 mL
マトリックス活性基
Macroporous polymer
ポアサイズ
0.4 μm pore size
キャパシティ
23 g binding capacity (BSA)(per device
per device)
分離法
strong anion exchange
輸送温度
ambient
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詳細
Strong anion exchange chromatography membrane design to purify biomolecules with a high density of quaternary amine ligand the enables fast flow rates and high throughput at high loads while maintaining excellent impurity reduction
With a revolutionary three-dimensional macroporous hydrogel structure that provides a high density of binding sites and rapid mass transfer, Natrix®chromatography membranes deliver binding capacity that exceeds resin-based columns with fast flow rates typical of traditional membrane adsorbers. This combination of performance and speed in a single-use, plug-and-play device format enables low-risk, scalable solutions for efficient biomolecule purification
Natrix® Q chromatography membrane is a high productivity strong anion exchange membrane designed for biomolecule purification. The unique Natrix® Q chromatography membrane is a porous polyacrylamide hydrogel containing a high density of pendant quaternary ammonium (Q) binding groups that are directly polymerized within the an inert, macroporous membrane scaffold. The interconnected pore structure and high functional group density enables fast flow rates (seconds of residence time) with impressive throughput to extremely high loads while maintaining excellent impurity reduction across a wide range of buffer conditions. The Natrix® Q chromatography membrane design delivers improvements in productivity, flexibility, and process robustness and economics for any bioprocess design. The Natrix® Q Process 150 is process scale device designed for full-scale clinical and commercial manufacturing.
mAb nominal polishing capacity: 1150 g
Membrane configuration: Pleated
1 device per package
Natrix® Q chromatography membrane is a high productivity strong anion exchange membrane designed for biomolecule purification. The unique Natrix® Q chromatography membrane is a porous polyacrylamide hydrogel containing a high density of pendant quaternary ammonium (Q) binding groups that are directly polymerized within the an inert, macroporous membrane scaffold. The interconnected pore structure and high functional group density enables fast flow rates (seconds of residence time) with impressive throughput to extremely high loads while maintaining excellent impurity reduction across a wide range of buffer conditions. The Natrix® Q chromatography membrane design delivers improvements in productivity, flexibility, and process robustness and economics for any bioprocess design. The Natrix® Q Process 150 is process scale device designed for full-scale clinical and commercial manufacturing.
mAb nominal polishing capacity: 1150 g
Membrane configuration: Pleated
1 device per package
特徴および利点
Natrix® Q membrane adsorber provides users with:
- High density of quaternary amine binding sites enabling rapid mass transfer
- High binding capacity even at fast flow rates
- Combination of performance and speed in, single use, plug-and-play device format enables low risk, scalable solutions for efficient biomolecule purification.
包装
Double bagged
法的情報
NATRIFLO is a trademark of Merck KGaA, Darmstadt, Germany
NATRIX is a registered trademark of Merck KGaA, Darmstadt, Germany
関連製品
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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資料
Pros and Cons of Existing Chromatography Technology
Membrane adsorbers are a cost-effective, robust, single-use solution for monoclonal antibody polishing
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