MABC282

Anti-BAG3 Antibody, clone AC-1

clone AC-1, from mouse

• 別名: BAG family molecular chaperone regulator 3, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, Docking protein CAIR-1
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: AC-1, monoclonal
• 化学種の反応性: human
• テクニック: immunohistochemistry: suitable (paraffin); immunoprecipitation (IP): suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NP_004272
• UniProtアクセッション番号: O95817
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... BAG3(9531)

詳細

詳細

Bcl2-associated athanogene 3 (BAG3), also known as CAIR-1 or Bis, belongs to a family of six evolutionarily conserved co-chaperone proteins that contain a characteristic C-terminal BAG domain. In most cell types, BAG3 is localized to the cytoplasm, where it regulates the heat shock protein 70 chaperone. BAG3 is activated in response to stressful stimuli, and plays a critical role in modulating multiple cellular processes, including apoptosis, autophagy, embryonic development, and actin rearrangement. Abnormal expression of BAG3 results cardiomyopathy dilated type 1HH.

アプリケーション

Detect BAG3 using this Anti-BAG3 Antibody, clone AC-1 validated for use in Immunoprecipitation, IHC(P).

品質

Evaluated by Immunoprecipitation in HeLa cell lysate.

Immunoprecipitation Analysis: 10 µg of this antibody immunoprecipitated BAG3 from HeLa cell lysate.

ターゲットの説明

~62 kDa observed

物理的形状

Format: Purified

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable