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Merck

HADK2MAG-61K

Millipore

MILLIPLEX® Human Adipokine Magnetic Bead Panel 2 - Endocrine Multiplex Assay

The Human Adipokine Magnetic Bead Panel 2, using the Luminex xMAP technology, enables the simultaneous analysis of nine protein biomarkers in human serum and plasma samples.

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.47

品質水準

交差性

human

メーカー/製品名

Milliplex®

assay range

accuracy: 87%
(IL-8)

accuracy: 91%
(TNFα)

accuracy: 94%
(Insulin)

standard curve range: 0.64-10,000 pg/mL
(IL-8)

standard curve range: 0.64-10,000 pg/mL
(NGF)

standard curve range: 0.64-10,000 pg/mL
(TNF-α)

standard curve range: 0.96-15,000 pg/mL
(IL-6)

standard curve range: 1.3-20,000 pg/mL
(IL-1β)

standard curve range: 1.3-20,000 pg/mL
(MCP-1)

standard curve range: 38-600,000 pg/mL
(Leptin)

standard curve range: 9.6-150,000 pg/mL
(HGF)

standard curve range: 9.6-150,000 pg/mL
(Insulin)

inter-assay cv: <15%
intra-assay cv: <10%
(IL-1β)

inter-assay cv: <15%
intra-assay cv: <10%
(IL-6)

inter-assay cv: <15%
intra-assay cv: <10%
(IL-8)

inter-assay cv: <15%
intra-assay cv: <10%
(Insulin)

inter-assay cv: <15%
intra-assay cv: <10%
(Leptin)

inter-assay cv: <15%
intra-assay cv: <10%
(MCP-1)

inter-assay cv: <15%
intra-assay cv: <10%
(NGF)

inter-assay cv: <20%
intra-assay cv: <10%
(TNFα)

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

Previously the role of white adipose tissue was thought to be limited to energy storage and internal organ protection. The discovery of Leptin secretion from Adipocytes in 1994 led to the recognition that white adipose tissue is involved in a variety of metabolic and physiological processes. Adipocytes secrete several hormones called Adipokines with functions that include appetite and energy balance, insulin sensitivity and lipid metabolism.

The MILLIPLEX® Human Adipokine Panel 2 is a 9-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum or plasma samples: HGF, IL-1β, IL-6, IL-8, Insulin, Leptin, MCP-1, NGF and TNF-α. This kit uses a 96-well format, contains a lyophilized standard cocktail, 2 quality controls and can measure up to 38 samples in duplicate.

Panel Type: Metabolism

特異性

Cross Reactivty
Each antibody pair in a panel is highly specific and displays insignificant cross-reactivity to other analytes in the panel.

アプリケーション

  • Analytes: IL-1β, IL-6, IL-8, Insulin, Leptin, MCP-1, NGF, TNF-α
  • Recommended Sample Type: Human serum and plasma
  • Recommended Sample Dilution: 25 μL per well of undiluted serum or plasma
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C
  • Research Category: Metabolism
  • Research Subcategory: Endocrine

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

包装

Everything you need in a single kit.
96-well plate

保管および安定性

Recommended storage for kit components is 2 - 8°C.

その他情報

Please contact Technical Service for linearity of dilution.
Sensitivity: See kit protocol for individual sensitives.

法的情報

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

ピクトグラム

Skull and crossbonesEnvironment

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

保管分類コード

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

毒物及び劇物取締法

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PRTR

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消防法

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労働安全衛生法名称等を表示すべき危険物及び有害物

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労働安全衛生法名称等を通知すべき危険物及び有害物

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カルタヘナ法

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Jan Code

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試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Waist-to-height ratio, waist circumference and BMI as indicators of percentage fat mass and cardiometabolic risk factors in children aged 3-7 years.
Sijtsma, A; Bocca, G; L'abee, C; Liem, ET; Sauer, PJ; Corpeleijn, E
Clinical Nutrition (Edinburgh, Scotland) null
Insulin resistance is associated with Fibroblast Growth Factor-23 in stage 3-5 chronic kidney disease patients.
Garland, JS; Holden, RM; Ross, R; Adams, MA; Nolan, RL; Hopman, WM; Morton, AR
Journal of Diabetes and Its Complications null
Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass.
Kirchner, H; Nylen, C; Laber, S; Barres, R; Yan, J; Krook, A; Zierath, JR; Naslund, E
Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery null
Yuek Ling Chai et al.
Scientific reports, 11(1), 4010-4010 (2021-02-19)
Cerebrovascular disease (CeVD) and neurodegenerative dementia such as Alzheimer's disease (AD) are frequently associated comorbidities in the elderly, sharing common risk factors and pathophysiological mechanisms including neuroinflammation. Osteopontin (OPN) is an inflammatory marker found upregulated in vascular diseases as well
Maria A Ramos-Roman et al.
Diabetes, 69(8), 1624-1635 (2020-05-10)
Milk production may involve a transient development of insulin resistance in nonmammary tissues to support redistribution of maternal macronutrients to match the requirements of the lactating mammary gland. In the current study, adipose and liver metabolic responses were measured in

関連コンテンツ

Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.

MILLIPLEX®マルチプレックス代謝アッセイなどのマルチプレックス・イムノアッセイは、メタボリックシンドローム研究に重要です。糖尿病や肥満など、関連するさまざまな病態の全体像を把握でき、時間とサンプル量を節約できるためです。

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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