GF176

TGF-β-III Protein, Human Recombinant

TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily.

• 別名: Transforming Growth Factor Beta 3, TGF-Beta-3, TGF-Beta-III
• UNSPSCコード: 12352202
• eCl@ss: 32160405
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: >98% (SDS-PAGE and HPLC)
• 不純物: <0.1 μg/mg protein endotoxin (<1 EU/μg)
• UniProtアクセッション番号: P10600
• 輸送温度: dry ice
• 遺伝子情報: human ... TGFB3(7043)

詳細

詳細

Product Source: E. coli.

TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily. TGF-β-I, TGF-β-II and TGF-β-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-β3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-β-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

アプリケーション

Research Category
幹細胞研究

Research Sub Category
成長因子及び受容体

品質

Determined by TGF-β-III’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.

物理的形状

Product is filtered through a 0.2 micron filter before lyophilization.

保管および安定性

Store at -20°C for up to 6 months from date of receipt.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable