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品質水準
製品種目
NovaSyn® TG
Novabiochem®
形状
beads
反応適合性
reaction type: Fmoc solid-phase peptide synthesis
メーカー/製品名
Novabiochem®
アプリケーション
peptide synthesis
保管温度
2-8°C
関連するカテゴリー
詳細
NovaSyn TG bromo resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol [1,2,3], in which the ends of the PEG chains have been bromo functionalized. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling properties across a wide range of solvents from toluene to water, making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis. This support may be used for the immobilization of alcohols, carboxylic acids, phenols and thiols, or as base support for other linkers [4,5]. Loading of this support can be carried out using the same methods as those previously described for Merrifield resin.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30, 113.
[4] K. H. Gordon & S. Balasubramanian (2001) Org. Lett., 3, 53.
[5] D. Tumelty, et al. (2001) Org. Lett., 3, 83
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30, 113.
[4] K. H. Gordon & S. Balasubramanian (2001) Org. Lett., 3, 53.
[5] D. Tumelty, et al. (2001) Org. Lett., 3, 83
関連事項
Replaces: 01-64-0095
アナリシスノート
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemntal analysis of bromine): 0.20 - 0.40 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
Appearance of substance (visual): beads
Loading (determined by elemntal analysis of bromine): 0.20 - 0.40 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
法的情報
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類コード
11 - Combustible Solids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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