5.43899

NMP

for liquid chromatography LiChrosolv^®

• 別名: 1-Methyl-2-pyrrolidone, NMP, N-Methyl-2-pyrrolidone
• 実験式（ヒル表記法）: C₅H₉NO
• CAS番号: 872-50-4
• 分子量: 99.13
• MDL番号: MFCD00003193
• UNSPSCコード: 41116105
• EC Index Number: 212-828-1
• NACRES: NA.03

特性

• product name: 1-Methyl-2-pyrrolidone, for liquid chromatography LiChrosolv^®
• 蒸気圧: 0.32 hPa ( 20 °C)
• 品質水準: 100
• 製品種目: LiChrosolv^®
• グレード: isocratic
• アッセイ: ≥99.5% (GC)
• 形状: liquid
• 自己発火温度: 245 °C
• expl. lim.: 1.3-9.5 % (v/v)
• テクニック: HPLC: suitable
• 不純物: ≤0.05% Water
• 透過率: 300 nm, ≥50%; 325 nm, ≥90%; 350 nm, ≥97%; 400 nm, ≥99%
• pH: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• bp: 202 °C/1013 hPa
• mp: -24 °C
• 転移温度: flash point 91 °C
• 溶解性: 1000 g/L
• 密度: 1.03 g/cm³ at 20 °C
• 保管温度: 2-30°C
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• InChI Key: SECXISVLQFMRJM-UHFFFAOYSA-N

詳細

アプリケーション

• Novel transdermal bioadhesive surfactant-based system for release and solubility improvement of antimalarial drugs artemether-lumefantrine: This study utilizes 1-Methyl-2-pyrrolidone (NMP) as a high-purity solvent in the formulation of a transdermal bioadhesive system, enhancing the solubility and delivery of antimalarial drugs. The application highlights NMP′s role in pharmaceutical formulations, particularly in improving drug efficacy and patient compliance (Volpe-Zanutto et al., 2021).

アナリシスノート

Purity (GC): ≥ 99.5 %
Water: ≤ 0.05 %
Transmission (at 300 nm): ≥ 50 %
Transmission (at 325 nm): ≥ 90 %
Transmission (at 350 nm): ≥ 97 %
Transmission (at 400 nm): ≥ 99 %

その他情報

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

法的情報

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS07,GHS08
• シグナルワード: Danger
• 危険有害性情報: H315 - H319 - H335 - H360D
• 注意書き: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• 引火点(°F): 195.8 °F - Pensky-Martens closed cup
• 引火点(℃): 91 °C - Pensky-Martens closed cup