528208

Plasminogen Activator Inhibitor-1, Mutant

from Recombinant, ≥95% (SDS-PAGE), liquid, PAI-1 inhibitor, Calbiochem^®

• 別名: PAI-1, Mutant
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 製品名: Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant, The Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant controls the biological activity of Plasminogen Activator. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
• 品質水準: 100
• アッセイ: ≥95% (SDS-PAGE)
• フォーム: liquid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; avoid repeated freeze/thaw cycles
• 輸送温度: wet ice
• 保管温度: −70°C

詳細

詳細

Highly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t_½ = 145 hours at 37°C, pH 7.4). Inhibits uPA (K_i = 5.1 x 10⁶ M^-1 sec^-1) and tPA (K_i = 7.9 x 10⁵ M^-1 sec^-1).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Plasminogen Activator

Product does not compete with ATP.

Reversible: no

Target K_i: 5.1 x 106 M-1 sec-1, 7.9 x 105 M-1 sec-1 against uPA and tPA, respectively

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

物理的形状

In 100 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.

再構成

Following initial thaw, aliquot and freeze (-70°C).

その他情報

Berkenpas, M.B., et al. 1995. EMBO J. 14, 2969.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable