5.00299

Nicotinamide

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC

• 別名: Nicotinamide, Nicotinamide, Niacinamide, 3-Pyridinecarboxamide
• 実験式（ヒル表記法）: C₆H₆N₂O
• CAS番号: 98-92-0
• 分子量: 122.12
• MDL番号: MFCD00006395
• UNSPSCコード: 12352111
• EC Index Number: 202-713-4

特性

• 認証: BP; JP; Ph. Eur.; USP
• 品質水準: 500
• 法規制遵守: FCC
• 詳細: EMPROVE^® ESSENTIAL Ph Eur,BP,USP,JP,FCC
• 製品種目: EMPROVE^® ESSENTIAL
• フォーム: solid
• 自己発火温度: 480 °C
• 有効性: 3530-3540 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rabbit)
• テクニック: API processing | cocrystal formation: suitable
• pH: 6.0-7.5 (20 °C, 50 g/L in H₂O)
• bp: 150-160 °C/0.0007 hPa
• mp: 128-131 °C (sublimed)
• 転移温度: flash point 182 °C
• 密度: 1.40 g/cm³ at 20 °C
• アプリケーション: liquid formulation; pharmaceutical; solid formulation
• 保管温度: 15-25°C
• SMILES記法: NC(=O)c1cnccc1
• InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
• InChI Key: DFPAKSUCGFBDDF-UHFFFAOYSA-N

詳細

詳細

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

Nicotinamide is a commonly used ingredient in food and pharmaceutical applications. In pharmaceutical formulations, nicotinamide has been used for a range of different dosage forms.

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H319
• 注意書き: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): 302.0 °F - closed cup
• 引火点(℃): 150 °C - closed cup