459616

Okadaic Acid, Ammonium Salt

Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.

• 別名: Okadaic Acid, Ammonium Salt
• 実験式（ヒル表記法）: C₄₄H₆₇O₁₃ · NH₄
• CAS番号: 155716-06-6
• 分子量: 822.03
• MDL番号: MFCD00153856
• UNSPSCコード: 12352106
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (TLC)
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: white
• 溶解性: water: 1 mg/mL; DMSO: 20 mg/mL; ethanol: 20 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: [N+H4].[O-]C(=O)[C@](O)(C[C@H]1O[C@]2(O[C@@H](CC(=C2)C)[C@H](C)\C=C\[C@@H]3O[C@@]4(O[C@H]5[C@@H](C(=C)[C@H](OC5CC4)[C@@H](O)C[C@@H](C6O[C@]7(OCCCC7)CC[C@H]6C)C)O)CC3)[C@@H](CC1)O)C
• InChI: 1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1
• InChI Key: ZBOMSHVRJSJGNR-JBNKPAQWSA-N

詳細

詳細

Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
PP1, PP2A

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Toxic (F)

その他情報

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Gjertsen, B.T., et al. 1994. J. Cell Sci.107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differentiation5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun.197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun.189, 950.
Kreienbuhl, P., et al. 1992. Blood80, 2911.
Normura, M., et al. 1992. Biochemistry31, 11915.
Song, Q., et al. 1992. J. Cell Physiol.153, 550.
Tada, T., et al. 1992. Immunopharmacol.24, 17.
Cohen, P., et al. 1990. Trends Biochem. Sci.15, 98.
Cohen, P., et al. 1989. Annu. Rev. Biochem.58, 453.
Cohen, P., and Cohen, P.T.W. 1989. J. Biol. Chem.264, 21435.
Haystead, T.A.J., et al. 1989. Nature337, 78.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301 + H311 + H331,H315
• 注意書き: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3